Marine Microbes Related Metabolic Studies

Dear Colleagues,

Oceans cover over 70% of the earth. The largely unexplored marine world that presumably harbors the most biodiversity may be the vastest resource to discover secondary metabolites, exhibiting a wide range of pharmaceutically relevant bioactivities. Among the marine organisms, marine bacteria and fungi have shown to produce novel natural products with unique and diverse chemical structures. Therefore, the marine-microbe-related natural products can crucially develop novel drugs or drug leads. Recently, the application of new interdisciplinary approaches, such as bioinformatics and genome mining, MS-based metabolomics, ribosome engineering, and heterologous expression, have a significant boost on the exploration of novel functional biomolecules from these microbes and the huge chemical potential of marine sources.

This Special Issue of Metabolites welcomes both fundamental research papers and critical review works covering the lastest develpments of marine microbes related metabolic studies, including on the discovery, the structure elucidation, and the in vitro and in vivo bioactivity evaluation of biosynthetic pathways and pharmaceutical mechanisms, as well as the metabolic engineering of marine natural products. In addition, manuscripts describing innovative methodological approaches for the screening and discovery of marine-microbe-related compounds are highly welcome. This Special Issue intends collect groundbreaking contributions in this field.

Prof. Dr. Fan Zhang
Prof. Dr. Fei Gan
Guest Editors

Manuscript Submission Information

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