Emerging Inflammatory and Metabolic Biomarkers in Hayfever
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: 15 August 2026 | Viewed by 303
Special Issue Editors
Interests: ocular allergy-clinical tests; metabolomics; lipidomics and epigenetics; ocular allergy with lived-experience
Interests: ocular allergy-clinical tests; metabolomics; lipidomics and epigenetics; ocular allergy with lived-experience
Interests: critically ill patients; micronutrients; vitamins; minerals; nutritional assessment; requirements; biomarkers; antioxidants; oxidative stress; inflammation; infection; supplementation; metabolism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hay fever is a chronic condition that is estimated to affect approximately 30% of the population. Changing climatic patterns and increasing temperatures are leading to changes in vegetation. Over the years, the hay fever season has become longer and has started to lead to more intense allergic reactions. Hay fever is a debilitating lifelong condition that is often underestimated, since sufferers quietly manage the condition without work absenteeism. Those who suffer from hay fever report reduced quality of sleep, a decrease in work productivity, an emotional burden, limitations to their outdoor activities, and an overall decrease in quality of life. Long-standing and/or severe hay fever is known to lead to asthma, which requires constant medical attention. Further, in severe weather conditions, this can perpetuate as a life-threatening condition called thunderstorm asthma, which has been documented globally in over 26 major events.
Currently, a diagnosis of hay fever is made purely based on the hallmark symptoms of sneezing, an itchy throat, and itchy eyes. The only confirmation test available is the invasive skin prick test. There is work in progress across multiple research areas to evaluate the levels of IgE in various bodily fluids such as saliva, the nose, and the eyes to develop a more tangible diagnostic test. Currently, there is no cure for hay fever. Thus, the majority of sufferers report self-managing their symptoms through over-the-counter oral antihistamines, nasal sprays, inhalers, and anti-allergy eye drops, and a minority undertake immunotherapy to reduce their symptoms.
This Special Issue presents a unique opportunity to bring together state-of-the-art research across disciplines for the diagnosis and management of hay fever. The scope of this Special Issue will encompass the following: the use of metabolomics to discover small-molecule metabolic biomarkers for the early diagnosis of allergic rhinitis; investigations into the impact of pollen exposure on metabolic flux; energy metabolism, or oxidative stress pathways in respiratory epithelial cells; and reports on the downstream effects of genetic and environmental perturbations on metabolite levels and fluxes, as hay fever is driven by both genetics and the environment. We welcome original articles, short communications, reviews, and perspectives that highlight new discoveries in hay fever or allergic rhinitis.
Dr. Moneisha Gokhale
Dr. Serap Azizoǧlu
Prof. Dr. Elena Planells
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- IgE sensitisation
- allergic rhinitis
- allergenic capacity
- thunderstorm asthma
- asthma
- immunotherapy
- indoor air quality
- questionnaire survey
- quality of life
- lived experience
- hayfever
- allergic rhinitis
- ocular allergy
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