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Announcements
5 March 2025
Metabolites | Hot Topic Papers Published in 2023–2024 in the “Advances in Metabolomics” Section

1. “Tryptophan Metabolism and Gut Microbiota: A Novel Regulatory Axis Integrating the Microbiome, Immunity, and Cancer”
by Yingjian Hou, Jing Li and Shuhuan Ying
Metabolites 2023, 13(11), 1166; https://doi.org/10.3390/metabo13111166
Available online: https://www.mdpi.com/2218-1989/13/11/1166
2. “Simultaneous Quantitation and Discovery (SQUAD) Analysis: Combining the Best of Targeted and Untargeted Mass Spectrometry-Based Metabolomics”
by Bashar Amer, Rahul R. Deshpande and Susan S. Bird
Metabolites 2023, 13(5), 648; https://doi.org/10.3390/metabo13050648
Available online: https://www.mdpi.com/2218-1989/13/5/648
3. “Explainable Artificial Intelligence Paves the Way in Precision Diagnostics and Biomarker Discovery for the Subclass of Diabetic Retinopathy in Type 2 Diabetics”
by Fatma Hilal Yagin, Seyma Yasar, Yasin Gormez, Burak Yagin, Abdulvahap Pinar, Abedalrhman Alkhateeb and Luca Paolo Ardigò
Metabolites 2023, 13(12), 1204; https://doi.org/10.3390/metabo13121204
Available online: https://www.mdpi.com/2218-1989/13/12/1204
4. “Is Lipid Metabolism of Value in Cancer Research and Treatment? Part II: Role of Specialized Pro-Resolving Mediators in Inflammation, Infections, and Cancer”
by Muhammad Usman Babar, Ala F. Nassar, Xinxin Nie, Tianxiang Zhang, Jianwei He, Jacky Yeung, Paul Norris, Hideki Ogura, Anne Muldoon, Lieping Chen et al.
Metabolites 2024, 14(6), 314; https://doi.org/10.3390/metabo14060314
Available online: https://www.mdpi.com/2218-1989/14/6/314
5. “Analysis of the Fecal Metabolomic Profile in Breast vs. Different Formula Milk Feeding in Late Preterm Infants”
by Giuseppe De Bernardo, Gilda D’Urso, Simona Spadarella, Maurizio Giordano, Giuseppina Leone and Agostino Casapullo
Metabolites 2024, 14(1), 72; https://doi.org/10.3390/metabo14010072
Available online: https://www.mdpi.com/2218-1989/14/1/72
6. “Changes in Plasma Free Amino Acid Profile in Endurance Athletes over a 9-Month Training Cycle”
by Krzysztof Kusy, Monika Ciekot-Sołtysiak, Jan Matysiak, Agnieszka Klupczyńska-Gabryszak, Szymon Plewa, Ewa Anna Zarębska, Zenon J. Kokot, Paweł Dereziński and Jacek Zieliński
Metabolites 2024, 14(7), 353; https://doi.org/10.3390/metabo14070353
Available online: https://www.mdpi.com/2218-1989/14/7/353
7. “Identification of Spatial Specific Lipid Metabolic Signatures in Long-Standing Diabetic Kidney Disease”
by Yiran Zhang, Hai-Long Piao and Di Chen
Metabolites 2024, 14(11), 641; https://doi.org/10.3390/metabo14110641
Available online: https://www.mdpi.com/2218-1989/14/11/641
8. “Longitudinal Metabolomics Data Analysis Informed by Mechanistic Models”
by Lu Li, Huub Hoefsloot, Barbara M. Bakker, David Horner, Morten A. Rasmussen, Age K. Smilde and Evrim Acar
Metabolites 2025, 15(1), 2; https://doi.org/10.3390/metabo15010002
Available online: https://www.mdpi.com/2218-1989/15/1/2
9. “Bioactive Metabolite Survey of Actinobacteria Showing Plant Growth Promoting Traits to Develop Novel Biofertilizers”
by Teresa Faddetta, Giulia Polito, Loredana Abbate, Pasquale Alibrandi, Marcello Zerbo, Ciro Caldiero, Chiara Reina, Guglielmo Puccio, Edoardo Vaccaro, Maria Rosa Abenavoli et al.
Metabolites 2023, 13(3), 374; https://doi.org/10.3390/metabo13030374
Available online: https://www.mdpi.com/2218-1989/13/3/374
10. “Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content”
by Zachary A. Kipp, Genesee J. Martinez, Evelyn A. Bates, Agil B. Maharramov, Robert M. Flight, Hunter N. B. Moseley, Andrew J. Morris, David E. Stec and Terry D. Hinds
Metabolites 2023, 13(2), 215; https://doi.org/10.3390/metabo13020215
Available online: https://www.mdpi.com/2218-1989/13/2/215
11. “VAMS-Based Blood Capillary Sampling for Mass Spectrometry-Based Human Metabolomics Studies”
by Chiara Volani, Christa Malfertheiner, Giulia Caprioli, Søren Fjelstrup, Peter P. Pramstaller, Johannes Rainer and Giuseppe Paglia
Metabolites 2023, 13(2), 146; https://doi.org/10.3390/metabo13020146
Available online: https://www.mdpi.com/2218-1989/13/2/146
12. “Serum-Based Lipid Panels for Diagnosis of Idiopathic Parkinson’s Disease”
by Lina A. Dahabiyeh, Refat M. Nimer, Maha Rashed, Jeremiah D. Wells and Oliver Fiehn
Metabolites 2023, 13(9), 990; https://doi.org/10.3390/metabo13090990
Available online: https://www.mdpi.com/2218-1989/13/9/990
13. “Life-Threatening Cardiogenic Shock Related to Venlafaxine Poisoning—A Case Report with Metabolomic Approach”
by Romain Magny, Bruno Mégarbane, Pauline Guillaud, Lucie Chevillard, Nicolas Auzeil, Pauline Thiebot, Sebastian Voicu, Isabelle Malissin, Nicolas Deye, Laurence Labat et al.
Metabolites 2023, 13(3), 353; https://doi.org/10.3390/metabo13030353
Available online: https://www.mdpi.com/2218-1989/13/3/353
14. “mGWAS-Explorer 2.0: Causal Analysis and Interpretation of Metabolite–Phenotype Associations”
by Le Chang, Guangyan Zhou and Jianguo Xia
Metabolites 2023, 13(7), 826; https://doi.org/10.3390/metabo13070826
Available online: https://www.mdpi.com/2218-1989/13/7/826
15. “Gut Microbiota–Gut Metabolites and Clostridioides difficile Infection: Approaching Sustainable Solutions for Therapy”
by Bijay Gurung, Maranda Stricklin and Shaohua Wang
Metabolites 2024, 14(1), 74; https://doi.org/10.3390/metabo14010074
Available online: https://www.mdpi.com/2218-1989/14/1/74