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Numerical Analysis in Medicine and Its Application in Biomaterials

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (20 February 2023) | Viewed by 2598

Special Issue Editors


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Guest Editor
Department of Oral Surgery, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland
Interests: fractal dimension analysis; texture analysis; numerical analysis; photodynamic therapy; photodynamic diagnosis; fluorescence; photobiology; lasers in medicine; oral potentially malignant lesions; oral surgery

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Guest Editor
Department of Maxillofacial Surgery, Medical University of Lodz, 113 Żeromskiego Str., 90-549 Lodz, Poland
Interests: maxillofacial surgery; traumatology; deformation treatment; head and neck oncology; infections treatment; human orbital reconstructions; mandibular condyle fixing material; custom-made temporomandibular joint replacements; bone substitute materials; implantology; surgery-first facial deformation algorithm
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Special Issue Information

Dear Colleagues,

Modern numerical analyses are most commonly applied in medicine and related branches. In common practice we are used to applying Euclidian geometry, but this classical method shows its disadvantages in the case of complicated shapes/patterns analyses. Such patterns are observed in the case of the microstructure of biomaterials, bone, skin, lesions, etc. Euclidian geometry may fail in these cases. Advanced algorithms of image analysis, such as fractal dimension analysis or texture analysis, may be helpful, especially in regard to the correlation of their results with easier measurable mechanical parameters, such as roughness, hardness, and flexibility. Another way to use the aforementioned methods is to implement them in computer-aided diagnosis systems.

The aim of this Special Issue is to focus on the application of modern mathematical methods, such as fractal dimension analysis, texture analysis, finite element analysis, radiomics, diagnostic data mining, etc., in medicine, primarily in regard to biomaterials and computer-aided diagnosis.

It is a pleasure to invite you to submit manuscripts to this Special Issue.

Dr. Kamil Jurczyszyn
Prof. Dr. Marcin Kozakiewicz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fractal dimension analysis
  • texture analysis
  • finite element analysis
  • radiomics
  • biomaterials
  • implants
  • biomaterials
  • materials
  • polymers
  • resorbable materials
  • surface analysis
  • microstructure analysis
  • computer-aided diagnosis
  • computer-aided design
  • surgery
  • oral surgery
  • craniofacial surgery
  • orthodontics
  • restorative dentistry
  • prosthetic dentistry

Published Papers (2 papers)

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Research

16 pages, 4623 KiB  
Article
Isolating the Role of Bone Lacunar Morphology on Static and Fatigue Fracture Progression through Numerical Simulations
by Federica Buccino, Francesco Cervellera, Marta Ghidini, Riccardo Marini, Sara Bagherifard and Laura Maria Vergani
Materials 2023, 16(5), 1931; https://doi.org/10.3390/ma16051931 - 26 Feb 2023
Cited by 2 | Viewed by 1088
Abstract
Currently, the onset of bone damage and the interaction of cracks with the surrounding micro-architecture are still black boxes. With the motivation to address this issue, our research targets isolating lacunar morphological and densitometric effects on crack advancement under both static and cyclic [...] Read more.
Currently, the onset of bone damage and the interaction of cracks with the surrounding micro-architecture are still black boxes. With the motivation to address this issue, our research targets isolating lacunar morphological and densitometric effects on crack advancement under both static and cyclic loading conditions by implementing static extended finite element models (XFEM) and fatigue analyses. The effect of lacunar pathological alterations on damage initiation and progression is evaluated; the results indicate that high lacunar density considerably reduces the mechanical strength of the specimens, resulting as the most influencing parameter among the studied ones. Lacunar size has a lower effect on mechanical strength, reducing it by 2%. Additionally, specific lacunar alignments play a key role in deviating the crack path, eventually slowing its progression. This could shed some light on evaluating the effects of lacunar alterations on fracture evolution in the presence of pathologies. Full article
(This article belongs to the Special Issue Numerical Analysis in Medicine and Its Application in Biomaterials)
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13 pages, 1285 KiB  
Article
Surface Evaluation of Aligners after Immersion in Coca-Cola and Orange Juice
by Maciej Warnecki, Michał Sarul, Marcin Kozakiewicz, Anna Zięty, Bartosz Babiarczuk, Beata Kawala and Kamil Jurczyszyn
Materials 2022, 15(18), 6341; https://doi.org/10.3390/ma15186341 - 13 Sep 2022
Cited by 8 | Viewed by 1631
Abstract
Orthodontic removable appliances made of transparent thermoplastic materials—aligners—are becoming increasingly popular in contemporary orthodontic practice. It is important for the clinician to fully understand the mechanical properties and behavior of the appliance used. Because of that, the aim of our study was to [...] Read more.
Orthodontic removable appliances made of transparent thermoplastic materials—aligners—are becoming increasingly popular in contemporary orthodontic practice. It is important for the clinician to fully understand the mechanical properties and behavior of the appliance used. Because of that, the aim of our study was to investigate the changes in aligner surface after immersion in Coca-Cola and orange juice. For surface evaluation, fractal analysis, texture analysis, and wetting angle measurement were performed. Statistically significant changes were found between some of the groups in the fractal dimension analysis. In texture analysis, all but one intergroup comparison showed statistically significant differences. For wetting angle assessment, statistically significant differences were found. These were, however, more numerous when assessing glycol droplets, rather than water droplets. Fractal dimension analysis confirmed a correlation between the intensity of changes in the aligner surface with immersion time in the liquids assessed. Texture analysis showed a high sensitivity to the changes in aligner surface. It failed, however, to reveal changes relative to immersion time. Wetting angle analysis revealed aligner surface degradation for Coca-Cola. It did not, however, prove the dependence of the intensity of this degradation as a function of time. Both Coca-Cola and orange juice can cause aligner surface degradation. Full article
(This article belongs to the Special Issue Numerical Analysis in Medicine and Its Application in Biomaterials)
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