Special Issue "Multifunctional Coatings for Bone Regenerative Medicine"
Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 5448
Interests: surface bio-functionalization; additive manufacturing and prevention of implant failures
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Aging population forces millions of people to undergo implant surgery for total hip and knee replacement, scoliosis, maxillofacial fixation, and traumatic condition. However, many of these implants fail due to (1) implant loosening: lack of necessary new bone formation to repair large bone defects or suitable integration with the existing bone and (2) implant-associated infection, despite a novel engineering design, sterilized operating theatre environment, and prophylaxis antibiotic therapy. To overcome these issues, different surface modification and coating strategies have been explored for decades. However, it remains a significant challenge to achieve an optimal biofunctionalized implant, mainly because they offer only a single functionality (either enhanced bone regeneration or antibacterial). On the other hand, because of recent progress in additive manufacturing technologies which allows researchers to design and fabricate rationally designed and topologically complex structures, it is now possible to introduce biomaterials with unprecedented combinations of mechanical, physical, and biological properties. Therefore, it is essential to focus on further developments in a new generation of biomaterials that offer multiple functionalities, including enhanced bone regeneration, infection prevention, and also render bespoke release profiles of the active agents to address unmet clinical needs.
This Special Issue aims to highlight the recent strategies in multifunctional coatings for bone regenerative medicine application. It is our pleasure to invite you to contribute your research article, communication or review for this Special Issue.
Dr. Saber AminYavari
Manuscript Submission Information
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- Multifunctional coatings
- Implant-associated infection
- Regenerative medicine
- Additive manufacturing