Special Issue "Multifunctional Coatings for Bone Regenerative Medicine"

A special issue of Materials (ISSN 1996-1944).

Deadline for manuscript submissions: 30 September 2020.

Special Issue Editor

Dr. Saber AminYavari
Guest Editor
Department of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands
Interests: surface bio-functionalization; additive manufacturing and prevention of implant failures
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Aging population forces millions of people to undergo implant surgery for total hip and knee replacement, scoliosis, maxillofacial fixation, and traumatic condition. However, many of these implants fail due to (1) implant loosening: lack of necessary new bone formation to repair large bone defects or suitable integration with the existing bone and (2) implant-associated infection, despite a novel engineering design, sterilized operating theatre environment, and prophylaxis antibiotic therapy. To overcome these issues, different surface modification and coating strategies have been explored for decades. However, it remains a significant challenge to achieve an optimal biofunctionalized implant, mainly because they offer only a single functionality (either enhanced bone regeneration or antibacterial). On the other hand, because of recent progress in additive manufacturing technologies which allows researchers to design and fabricate rationally designed and topologically complex structures, it is now possible to introduce biomaterials with unprecedented combinations of mechanical, physical, and biological properties. Therefore, it is essential to focus on further developments in a new generation of biomaterials that offer multiple functionalities, including enhanced bone regeneration, infection prevention, and also render bespoke release profiles of the active agents to address unmet clinical needs.

This Special Issue aims to highlight the recent strategies in multifunctional coatings for bone regenerative medicine application. It is our pleasure to invite you to contribute your research article, communication or review for this Special Issue.

Dr. Saber AminYavari
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Multifunctional coatings
  • Implant-associated infection
  • Osseointegration
  • Regenerative medicine
  • Additive manufacturing

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Tentative Title: The Potential of Clinically-Developed Adjuvants as Immune Enhancers of Orthopedic Implants
Authors:  Paree Khokhani 1; Nada Ristya Rahmani 1; Anne Kok 1; Koen Santing 1; Harrie Weinans 1; Jacqueline Alblas 1; Moyo Kruyt 1; J. van Strijp 2 and Michiel Croes 1
1 Department of orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands; (P.K.); (N.R.R.); (A.K.); (K.S.); (H.W.); (J.A.); (M.K.); (M.C.)
2 Department of medical microbiology, University Medical Center Utrecht, Utrecht, the Netherlands; (J.V.S.)

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