Special Issue "Biomaterials Used in Clinical Practice and Their Tribological Behaviours Assessed In Vitro, In Silico, and In Vivo"
Deadline for manuscript submissions: 30 June 2021.
Interests: biotribology; ceramic; metal; composite; biomaterials; hip; knee; simulator; in silico; prosthesis
Special Issues and Collections in MDPI journals
Special Issue in Materials: Advanced Biomaterials for Orthopaedic Application: The Challenge of New Composites and Alloys Used as Medical Devices
Special Issue in Materials: Metal and Ceramics Composite Materials for Prosthetic Hip and Knee Joint Replacement
It is a great pleasure to announce this Special Issue on “Biomaterials used in Clinical Practice and Their Tribological Behavior Assessed in Vitro, in Silico, and in Vivo”.
Joint replacement surgeries (hip, knee, ankle, etc.) are a successful and consolidated branch of orthopedics. The progressive achievement in alleviating pain and disability helps patients to return to an active life. Research in new biomaterials plays an important role, and as a consequence, in vitro and in silico tests for such materials are of great importance. The knowledge of the laboratory wear rate is an important aspect in the preclinical validation of prostheses. Research and development of wear-resistant materials continues to be a high priority in order to evaluate the performance of new materials intended to reduce wear, which is essential to ascertaining their efficacy and preventing the possibility of unexpected failure. Obviously, wear tests have a long duration, and they are very expensive. In recent years, “prediction of wear” in hip and knee replacements has been a subject of intense study. In silico investigation, where algorithms could be developed to model a biomedical process, is a logical extension of controlled in vitro experimentation. It is the natural result of the explosive increase in computing power available to scientists; thus, numerical models could be used to predict results of a wear test with less time and cost. Obviously, the in silico analysis integrates but does not replace the experimental tools. In silico methods based on musculoskeletal modeling simulations are powerful tools that allow biomechanical investigations and predictions of muscle forces not accessible with experiments; this allows us to develop subject-specific models able to simultaneously predict muscle, ligament, and knee joint contact forces, which may be used to test orthopedic implants with patient-specific load configuration. The in silico approach constitutes a promising methodology in arthroplasty, allowing the prediction of tribological phenomena in preclinical wear tests.
This international peer-reviewed open access journal is indexed by the Science Citation Index Expanded (Web of Science) ISSN: 1996-1944, Impact Factor: 2.972.
I hope to receive many interesting contributions.
Dr. Saverio Affatato
Manuscript Submission Information
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- Hip prostheses
- Knee prostheses
- Ankle prostheses
- SEM analyses
- Micro-CT analyses
- Temporary spacer
- Raman spectroscopy
- In silico simulation
- Multibody model