Special Issue "Bioactive Ceramics and Their Applications"

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 30 June 2020.

Special Issue Editor

Assoc. Prof. Lisa Biasetto
E-Mail Website
Guest Editor
Dipartimento di Tecnica e Gestione dei Sistemi Industriali, Università degli Studi di Padova, Padua, Italy
Interests: Ceramic bio-coatings, Direct Ink Writing, Scaffolds, Sustainable product development

Special Issue Information

Dear Colleagues,

Bioceramic materials are moving a step ahead: applications where ceramics were denied are becoming a reality, due to the evolution of novel compositions and manufacturing processes that produce materials possessing outstanding mechanical and bioactive properties. Beside the use of hydroxyapatite for bone repair, the recognized importance of silicon in the bone regeneration process has opened the door to silicon-substituted hydroxyapatite regarding calcium silicates and their solid solutions (i.e., with TiO2 and MgO).

These advances have given rise to a novel generation of bioceramic coatings possessing better adhesion and bioactivity than traditional hydroxyapatite-based ones. The advent of additive manufacturing technologies allows for the production of porous ceramic scaffolds with tailored geometry, pores, and roughness.

Bioceramic bone grafts can find applications in non-load-bearing implants such as maxillofacial surgery or connections in orthopedics and dentistry. Biocremics can also be used as fillers, like powders or spheres.

The use of bioceramics as coatings allows for the improvement of implant bioactivity where mechanical strength and elastoplasticity are the main prerequisites (orthopedic and dental applications).

This Special Issue wants to focus on state-of-the-art and cutting edge research on the three main applications of bioceramics: maxillofacial, orthopedic, and dental, to ensure that the four main bioceramics shapes are used: coatings, 3D printed scaffolds, foams, and powders and beads.

Assoc. Prof. Lisa Biasetto
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioceramics
  • scaffolds
  • coatings
  • implants
  • bone tissue regeneration

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Review

Open AccessArticle
Plasma-Sprayed Bioactive Ceramic Coatings with High Resorption Resistance Based on Transition Metal-Substituted Calcium Hexaorthophosphates
Materials 2019, 12(13), 2059; https://doi.org/10.3390/ma12132059 - 27 Jun 2019
Abstract
Calcium (titanium, zirconium) hexaorthophosphates with a [NZP] (sodium zirconium phosphate) structure belonging to the NaSiCon (Na Superionic Conductor) family were deposited by atmospheric plasma spraying onto the surfaces of Ti6Al4V substrates. (NaSiCon sensu strictu refers to solids with [...] Read more.
Calcium (titanium, zirconium) hexaorthophosphates with a [NZP] (sodium zirconium phosphate) structure belonging to the NaSiCon (Na Superionic Conductor) family were deposited by atmospheric plasma spraying onto the surfaces of Ti6Al4V substrates. (NaSiCon sensu strictu refers to solids with the chemical formula Na1+xZr2SixP3−xO12, 0 < x < 3. In a broader sense, it is also used for similar compounds where Na, Zr and/or Si are replaced by isovalent elements). The microstructure of the coatings revealed the incongruent melting of the precursor material as ascertained by electron probe microanalysis (EPMA). The adhesion of the coatings to the substrate surface was within the limits specified for biomedical coatings. The solubility of the coatings was tested by immersion in 0.2 molar tris–hydroxymethyl–amino–methane–HCl (TRIS–HCl) buffer and found to be at least one order of magnitude lower than that of conventional hydroxylapatite coatings deposited under comparable conditions. In vitro biocompatibility tests with primary rat bone marrow cells (BMCs) showed a substantial cell proliferation in the presence of fetal bovine serum. Animal tests confirmed that coatings based on calcium (titanium, zirconium) hexaorthophosphates applied to Ti6Al4V rods implanted in the femoral medulla of sheep led to the strong neoformation of dense bone at a stable interface implant-bioceramic coating without coating delamination. Hence, based on their multifarious advantageous properties in the biomedical context, CaTi4-xZrx(PO4)6 ceramics may be considered the ‘Sleeping Beauty’ of osseoconductive coatings for the stem of hip endoprostheses and dental root implants, osteosynthetic fixation devices, and bioelectric devices including bone growth stimulators. Full article
(This article belongs to the Special Issue Bioactive Ceramics and Their Applications)
Show Figures

Figure 1

Review

Jump to: Research

Open AccessReview
Bioactive Glass and Silicate-Based Ceramic Coatings on Metallic Implants: Open Challenge or Outdated Topic?
Materials 2019, 12(18), 2929; https://doi.org/10.3390/ma12182929 - 10 Sep 2019
Abstract
The overall success and long-term life of the medical implants are decisively based on the convenient osseointegration at the hosting tissue-implant interface. Therefore, various surface modifications and different coating approaches have been utilized to the implants to enhance the bone formation and speed [...] Read more.
The overall success and long-term life of the medical implants are decisively based on the convenient osseointegration at the hosting tissue-implant interface. Therefore, various surface modifications and different coating approaches have been utilized to the implants to enhance the bone formation and speed up the interaction with the surrounding hosting tissues, thereby enabling the successful fixation of implants. In this review, we will briefly present the main metallic implants and discuss their biocompatibility and osseointegration ability depending on their chemical and mechanical properties. In addition, as the main goal of this review, we explore the main properties of bioactive glasses and silica-based ceramics that are used as coating materials for both orthopedic and dental implants. The current review provides an overview of these bioactive coatings, with a particular emphasis on deposition methods, coating adhesion to the substrates and apatite formation ability tested by immersion in Simulated Body Fluid (SBF). In vitro and in vivo performances in terms of biocompatibility, biodegradability and improved osseointegration are examined as well. Full article
(This article belongs to the Special Issue Bioactive Ceramics and Their Applications)
Show Figures

Graphical abstract

Back to TopTop