Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
3.4
Journals
Materials
Special Issues
Antimicrobial Nanocomposites for Biomedical Applications
materials-logo
Submit to Materials Review for Materials Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Antimicrobial Nanocomposites for Biomedical Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (10 October 2023) | Viewed by 2959

Special Issue Editors

Dr. Carmen Steluţa Ciobanu

E-Mail Website
Guest Editor
National Institute of Materials Physics, 405A Atomistilor Street, P.O. Box MG7, 077125 Magurele, Romania
Interests: biomaterials; nanoparticles; iron oxide; hydroxyapatite; biomedical applications; physicochemical properties
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Ștefania Mariana Raită

E-Mail Website
Guest Editor Assistant
Faculty of Veterinary Medicine, University of Agronomical Sciences and Veterinary Medicine of Bucharest, 105 Splaiul Independentei, 050097 Bucharest, Romania
Interests: veterinary medicine; virology; cell biology; histology and embryology; bees’ health; anatomic pathology; biodiversity; nanotechnologies
Dr. Ciprian Florin Furnaris

E-Mail Website
Guest Editor Assistant
Faculty of Veterinary Medicine, University of Agronomical Sciences and Veterinary Medicine of Bucharest, 105 Splaiul Independentei, 050097 Bucharest, Romania
Interests: veterinary medicine; terrestrial and aquatic animal welfare and protection; veterinary hygiene; environmental protection; high tech in farming

Special Issue Information

Dear Colleagues,

One of the biggest concerns around the world today is the rapid development of antibiotic-resistant pathogens. It is well known that infections are difficult to treat due to the fact that the microorganisms involved can easily adapt to treatment with common antibiotics. In this context, the development of new antimicrobials based on nanocomposite biomaterials with antimicrobial properties is of great interest to the scientific community. This new type of antimicrobials could reduce the use of conventional antibiotics and the development of drug-resistant microbes in the healthcare domain, leading to a reduction in hospitalization costs and an improvement in patients’ quality of life.

This Special Issue will focus on new advances in the antimicrobial nanocomposite research domain. The main aim will be to highlight the latest advances in the development and complex characterization of new antimicrobial nanocomposites for biomedical application (infection prevention and treatment, prevention of bacterial colonization and biofilm formation, bone fillers, dentistry, wound dressings, drug delivery and other relevant applications). Therefore, we invite all colleagues to share contributions that include the development of antimicrobial nanocomposites, their complex characterization (physicochemical studies, biological evaluation, antimicrobial assays, etc.) and their potential biomedical applications.

In this Special Issue, original research articles and reviews are welcomed, presenting new advances and perspectives in the field of antimicrobial nanocomposites with biomedical applications.

Dr. Carmen Steluţa Ciobanu
Guest Editors

Prof. Dr. Ștefania Mariana Raită
Dr. Ciprian Florin Furnaris
Guest Editor Assistants

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial properties
  • nanocomposites
  • biomedical applications
  • biocompatibility
  • surface functionalization

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

12 pages, 3122 KiB  
Article
Antibacterial and Biocompatible Polyethylene Composites with Hybrid Clay Nanofillers
by Lenka Klecandová, Damian S. Nakonieczny, Magda Reli and Gražyna Simha Martynková
Materials 2023, 16(14), 5179; https://doi.org/10.3390/ma16145179 - 23 Jul 2023
Cited by 1 | Viewed by 1056
Abstract
Low-density polyethylene is one of the basic polymers used in medicine for a variety of purposes; so, the relevant improvements in functional properties are discussed here, making it safer to use as devices or implants during surgery or injury. The objective of the [...] Read more.
Low-density polyethylene is one of the basic polymers used in medicine for a variety of purposes; so, the relevant improvements in functional properties are discussed here, making it safer to use as devices or implants during surgery or injury. The objective of the laboratory-prepared material was to study the antimicrobial and biocompatible properties of low-density polyethylene composites with 3 wt. % hybrid nanoclay filler. We found that the antimicrobial activity was mainly related to the filler, i.e., the hybrid type, where inorganic clay minerals, vermiculite or montmorillonite, were intercalated with organic chlorhexidine diacetate and subsequently decorated with Ca-deficient hydroxyapatite. After fusion of the hybrid nanofiller with polyethylene, intense exfoliation of the clay layers occurred. This phenomenon was confirmed by the analysis of the X-ray diffraction patterns of the composite, where the original basal peak of the clays decreased or completely disappeared, and the optimal distribution of the filler was observed using the transmission mode of light microscopy. Functional property testing showed that the composites have good antibacterial activity against Staphylococcus aureus, and the biocompatibility prediction demonstrated the formation of Ca- and P-containing particles through an in vitro experiment, thus applicable for medical use. Full article
(This article belongs to the Special Issue Antimicrobial Nanocomposites for Biomedical Applications)
►▼ Show Figures

Figure 1

17 pages, 4121 KiB  
Article
Biological Response of Human Gingival Fibroblasts to Zinc-Doped Hydroxyapatite Designed for Dental Applications—An In Vitro Study
by Madalina Andreea Badea, Mihaela Balas, Marcela Popa, Teodora Borcan, Anamaria-Cristina Bunea, Daniela Predoi and Anca Dinischiotu
Materials 2023, 16(11), 4145; https://doi.org/10.3390/ma16114145 - 2 Jun 2023
Cited by 2 | Viewed by 1408
Abstract
This study aimed to investigate the biological response induced by hydroxyapatite (HAp) and zinc-doped HAp (ZnHAp) in human gingival fibroblasts and to explore their antimicrobial activity. The ZnHAp (with xZn = 0.00 and 0.07) powders, synthesized by the sol-gel method, retained the crystallographic [...] Read more.
This study aimed to investigate the biological response induced by hydroxyapatite (HAp) and zinc-doped HAp (ZnHAp) in human gingival fibroblasts and to explore their antimicrobial activity. The ZnHAp (with xZn = 0.00 and 0.07) powders, synthesized by the sol-gel method, retained the crystallographic structure of pure HA without any modification. Elemental mapping confirmed the uniform dispersion of zinc ions in the HAp lattice. The size of crystallites was 18.67 ± 2 nm for ZnHAp and 21.54 ± 1 nm for HAp. The average particle size was 19.38 ± 1 nm for ZnHAp and 22.47 ± 1 nm for HAp. Antimicrobial studies indicated an inhibition of bacterial adherence to the inert substrate. In vitro biocompatibility was tested on various doses of HAp and ZnHAp after 24 and 72 h of exposure and revealed that cell viability decreased after 72 h starting with a dose of 31.25 µg/mL. However, cells retained membrane integrity and no inflammatory response was induced. High doses (such as 125 µg/mL) affected cell adhesion and the architecture of F-actin filaments, while in the presence of lower doses (such as 15.625 µg/mL), no modifications were observed. Cell proliferation was inhibited after treatment with HAp and ZnHAp, except the dose of 15.625 µg/mL ZnHAp at 72 h of exposure, when a slight increase was observed, proving an improvement in ZnHAp activity due to Zn doping. Full article
(This article belongs to the Special Issue Antimicrobial Nanocomposites for Biomedical Applications)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop