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Relation Between Hydraulic Endodontic Sealers and Build Up of Endodontically Treated Teeth

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 412

Special Issue Editors


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Guest Editor
Department of Prosthodontics & Dental Material, University School of Dental Medicine, University of Siena, 53100 Siena, Italy
Interests: post; bonding; implants; prosthodontic materials
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
University School of Dental Medicine, University of Siena, 53100 Siena, Italy
Interests: endodontic; endodontic materials; endodontic sealers

Special Issue Information

Dear Colleagues,

In recent years, hydraulic endodontic sealers have been introduced in daily dentistry and have been well-received by endodontists and practitioners. Many in vitro studies have shown their chemical and mechanical properties, and other tests performed in vivo have shown their biological characteristics, clinical behavior, and outcomes. Almost all of these investigations concentrated on the “endodontic and biological aspects” of these new sealers, but the possible role of hydraulic endodontic sealers on the bonding steps required to build up endodontically treated teeth is still uncertain, and many questions have been raised by scientists and clinicians as well. Studies about bonding to root canal dentins, such as those on bond strength, leakage, radiopacity, compatibility among different types of hydraulic endodontic sealers with different bonding systems, procedures to clean the post space, type of restorative materials to be used, etc., are still yet to be performed. Lastly, randomized controlled trials are desirable to confirm (or not) lab findings. For this purpose, you are invited to contribute your valuable and important articles to this Special Issue.

Prof. Dr. Marco Ferrari
Guest Editor

Dr. Denise Pontoriero
Guest Editor Assistant

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Keywords

  • hydraulic endodontic sealers
  • bioceramic endodontic sealers
  • bonding to root dentin

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Published Papers (1 paper)

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Research

15 pages, 2675 KiB  
Article
Aloe Vera as an Adjunct in Endodontic Irrigation: Impact on Dentin Bond Strength and Cytotoxicity
by Lucas David Galvani, Ester Alves Ferreira Bordini, Diana Gabriela Soares, Joatan Lucas de Sousa Gomes Costa, José Rodolfo Verbicário, Fernando Pozzi Semeghini Guastaldi, Milton Carlos Kuga and Luís Geraldo Vaz
Materials 2025, 18(12), 2874; https://doi.org/10.3390/ma18122874 - 18 Jun 2025
Viewed by 205
Abstract
This study evaluated the effects of mechanical agitation of Aloe vera Barbadensis Miller solution at different concentrations using passive ultrasonic irrigation (PUI), XP Endo Finisher (XPF), XP Clean (XPC), and Easy Clean (ECL), compared to conventional endodontic irrigation (CIE), on bond strength and [...] Read more.
This study evaluated the effects of mechanical agitation of Aloe vera Barbadensis Miller solution at different concentrations using passive ultrasonic irrigation (PUI), XP Endo Finisher (XPF), XP Clean (XPC), and Easy Clean (ECL), compared to conventional endodontic irrigation (CIE), on bond strength and adhesive failure patterns in the cervical, middle, and apical thirds of the root canal. Aloe vera solutions at 1%, 3%, and 5% were tested to reverse collagen fiber collapse induced by hypochlorous acid, a free radical released by 2.5% sodium hypochlorite, which impairs dentin hybridization and the light curing of resin cement. Fiberglass posts were cemented using an etch-and-rinse adhesive system (Ambar; FGM) and conventional dual resin cement (Allcem Core) in root dentin across all thirds. Human teeth underwent chemical–mechanical preparation, and the Aloe vera solution was agitated using the CIE, PUI, XPF, XPC, or ECL protocols. Slices from each root third were evaluated under a stereomicroscope at 10× magnification and subjected to the push-out test. Cytotoxicity was assessed by applying various Aloe vera concentrations to stem cells from the apical papilla (SCAPs) for 24 h, followed by analysis of cell metabolism (Alamar Blue), viability (Live/Dead), and proliferation (F-actin). Aloe vera demonstrated significant biological activity and enhanced bond strength, particularly at 3% and 5%, irrespective of the agitation method or root third. Thus, it can be concluded that using Aloe vera solution is an alternative for pre-treatment before the cementation of fiberglass posts with conventional dual-cure resin cement in endodontically treated dentin. Full article
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