Advanced Magnetic Nanomaterial for Cancer Therapy and Diagnosis

A special issue of Magnetochemistry (ISSN 2312-7481). This special issue belongs to the section "Magnetic Materials".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 1685

Special Issue Editor


E-Mail Website
Guest Editor
Institute of Chemical Biology and Fundamental Medicine, Biomedical Chemistry laboratory, Russian Academy of Sciences, Novosibirsk, Lavrentyev Ave. 8, Russia
Interests: biomedical Imaging; drug-delivery systems; theranostics; anti-cancer drugs; medicinal chemistry; nanomaterials; nanocomposites; nuclear magnetic resonance; magnetic resonance imaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Magnetic nanoparticles and nanocomposites are promising highly functionalizable tools for cancer diagnosis, monitoring, and therapy. Studying magnetic nanospecies’ structural features and coating procedures and stability opens up excellent prospects for multifunctional and bioinspired materials and devices. The influence of magnetic fields can be used as an exogenous stimulus to induce changes in the physical, chemical, and structural properties. Therefore, magnetic nanocomposites synthesis, conjugation strategies to apply bioinspired construction for diagnosis, and simultaneous therapy have been a feature of the last several years. New prospects in the theranostics area will lead to obtaining a promising tool for clinics.

This Special Issue is focused on the most recent advances in the synthesis, characterization, and optimization of magnetic nanoparticle properties, surface coating for enhanced stability, biocompatibility, and toxicity in various areas such as diagnostics, imaging, drug–gene delivery, and therapy of cancer.

Dr. Alexey Chubarov
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Magnetochemistry is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanotechnology
  • magnetic nanoparticles
  • nanocomposites
  • multifunctional materials
  • biomaterials
  • magnetic resonance imaging
  • magnetic hyperthermia
  • drug delivery
  • therapy
  • diagnostics
  • theranostics
  • coatings
  • biocompatibility
  • toxicity

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 2870 KiB  
Article
Low-Frequency Dynamic Magnetic Fields Decrease Cellular Uptake of Magnetic Nanoparticles
by Anna V. Ivanova, Nelly S. Chmelyuk, Aleksey A. Nikitin, Alexander G. Majouga, Vladimir P. Chekhonin and Maxim A. Abakumov
Magnetochemistry 2024, 10(2), 9; https://doi.org/10.3390/magnetochemistry10020009 - 1 Feb 2024
Viewed by 1300
Abstract
Magnetic nanoparticles have gained attention as a potential structure for therapy and diagnosing oncological diseases. The key property of the magnetic nanoparticles is the ability to respond to an external magnetic field. It is known that magnetofection causes an increase in the cellular [...] Read more.
Magnetic nanoparticles have gained attention as a potential structure for therapy and diagnosing oncological diseases. The key property of the magnetic nanoparticles is the ability to respond to an external magnetic field. It is known that magnetofection causes an increase in the cellular uptake of RNA and DNA in complexes with magnetic nanoparticles in the presence of a permanent magnetic field. However, the influence of a dynamic magnetic field on the internalization of MNPs is not clear. In this work, we propose the idea that applying external low-frequency dynamic magnetic fields may decrease the cellular uptake, such as macrophages and malignant neuroblastoma. Using fluorescence microscopy and atomic emission spectroscopy, we found that oscillating magnetic fields decreased the cellular uptake of magnetic nanoparticles compared to untreated cells by up to 46%. In SH-SY5Y tumor cells and macrophage RAW264.7 cells, the absolute values of Fe per cell differed by 0.10 pg/cell and 0.33 pg/cell between treated and untreated cells, respectively. These results can be applied in the control of the cellular uptake in different areas of biomedicine. Full article
(This article belongs to the Special Issue Advanced Magnetic Nanomaterial for Cancer Therapy and Diagnosis)
Show Figures

Figure 1

Back to TopTop