Biomedical Composite Applications

A special issue of Journal of Composites Science (ISSN 2504-477X). This special issue belongs to the section "Biocomposites".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 553

Special Issue Editors


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Guest Editor
Facultad de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Tijuana 21500, Mexico
Interests: tissue engineering; drug delivery systems; biotechnology; nanotechnology; electrospinning; biosensors
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Instituto Tecnológico Superior de Acatlán de Osorio, Acatlán de Osorio 74949, Puebla, Mexico
Interests: carbon; nanocomposite

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Guest Editor
Biomedical Engineering Research Group—GBIO, Universidad Autónoma de Occidente, Cali 760030, Colombia
Interests: optoelectronics; biomaterials; bioengineering; drug delivery systems
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We would like to invite you to contribute to our Special Issue titled “Biomedical Composite Applications” in the Journal of Composites Science. This Special Issue aims to explore the rapidly advancing field of biomedical composites, which play a critical role in modern healthcare applications, including medical implants, drug delivery systems, tissue engineering, and diagnostic devices.

Biomedical composites, which integrate biocompatible materials with tailored mechanical, thermal, and biological properties, have revolutionized patient care by improving the functionality, durability, and performance of medical devices. Advances in polymer-based, ceramic-based, and metal-based composites, as well as the incorporation of nanomaterials, have led to breakthroughs in regenerative medicine, prosthetics, and antimicrobial coatings. By garnering cutting-edge research in this area, this Special Issue aims to highlight the latest innovations and their transformative potential in biomedical applications.

The Aim and Scope of the Special Issue

This Special Issue seeks to provide a platform for high-quality research that addresses both fundamental and applied aspects of biomedical composites. By showcasing novel materials, fabrication techniques, and their applications in medicine, this collection will contribute to the ongoing development of advanced healthcare solutions.

Aligned with the scope of the Journal of Composites Science, which focuses on the synthesis, characterization, and application of composite materials, this Special Issue will emphasize the following:

  • The design and optimization of biomedical composites for enhanced biocompatibility and mechanical performance.
  • Advanced processing techniques for biomedical composites, including additive manufacturing and nano structuring.
  • Functionalization strategies for improved antimicrobial, drug release, and tissue integration properties.
  • The theoretical modeling and experimental validation of composite materials in medical applications.

We aim to compile at least ten high-impact articles, and if this threshold is met, the collection may be published in book form to further amplify its reach within the scientific community.

Suggested Themes and Article Types

We welcome original research articles, review papers, case studies, and short communications on topics including, but not limited to, the following:

  • Polymer-based composites for medical applications (e.g., PLA, PLGA, PEEK, hydrogels);
  • Metallic and ceramic composites for implants and prosthetics;
  • Nanocomposite-based drug delivery systems and antimicrobial coatings;
  • Biodegradable and bioresorbable composite materials;
  • The additive manufacturing and 3D printing of biomedical composites;
  • Tissue engineering scaffolds and regenerative medicine applications;
  • Functional coatings and surface modifications for medical devices;
  • The computational modeling and simulation of biomedical composite performance.

Manuscripts should be prepared according to the journal’s submission guidelines and will undergo a rigorous peer-review process to ensure that the highest scientific standards are met. We look forward to receiving your contributions to this Special Issue and advancing the field through our collaborative efforts. 

Dr. Luis Jesús Villarreal-Gómez
Dr. Yoxkin Estévez-Martínez
Dr. Faruk Fonthal Rico
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Composites Science is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomedical composites
  • biocompatibility
  • medical applications
  • drug delivery systems
  • biodegradable and bioresorbable composite materials
  • tissue engineering
  • functional coatings and surface modifications

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Published Papers (2 papers)

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Research

16 pages, 2749 KiB  
Article
Collagen/Polypyrrole Biomimetic Electroactive Composite Coating with Fiber Network Structure on Titanium Surface for Bone Tissue Engineering
by Yuan Liang, Xin Xin, Xuzhao He, Wenjian Weng, Chengwei Wu and Kui Cheng
J. Compos. Sci. 2025, 9(7), 325; https://doi.org/10.3390/jcs9070325 - 24 Jun 2025
Viewed by 201
Abstract
Both biochemical cues and the electrophysiological microenvironment play a pivotal role in influencing cell behaviors. In this study, collagen/polypyrrole biomimetic electroactive composite coatings with a fiber network structure were constructed on the surface of titanium substrates by hot alkali treatment and stepwise electrochemical [...] Read more.
Both biochemical cues and the electrophysiological microenvironment play a pivotal role in influencing cell behaviors. In this study, collagen/polypyrrole biomimetic electroactive composite coatings with a fiber network structure were constructed on the surface of titanium substrates by hot alkali treatment and stepwise electrochemical deposition. Materialistic characterization and electrochemical performance tests demonstrated that the titanium electrodes modified with collagen/polypyrrole composite coatings exhibited the surface morphology of a collagen film layer, and their electroactivity was significantly enhanced. Cellular experiments demonstrated that the collagen in the composite coatings could provide good biomimetic biochemical cues as a main extracellular matrix component, which have a substantial effect in promoting cell adhesion, proliferation, and osteogenic differentiation. Furthermore, under exogenous electrical signals, the polypyrrole coating has the capacity to facilitate an appropriate electrophysiological microenvironment, thereby promoting osteogenic differentiation. The collagen/polypyrrole composite coating exhibited a better effect in promoting osteogenic differentiation among all samples by simultaneously providing the appropriate biochemical cues and electrophysiological microenvironments. This work demonstrates the feasibility of synergistic pro-osteogenesis by biochemical cues and an electrophysiological microenvironment, which is instructive for the field of bone tissue engineering. Full article
(This article belongs to the Special Issue Biomedical Composite Applications)
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13 pages, 3837 KiB  
Article
Effect of Surface Functional Groups and Calcium Ion Adsorption on Formation of Polystyrene/Apatite Core–Shell Microspheres by Aqueous Solution Method
by Takeshi Yabutsuka, Kota Nakanishi and Shigeomi Takai
J. Compos. Sci. 2025, 9(7), 323; https://doi.org/10.3390/jcs9070323 - 24 Jun 2025
Viewed by 200
Abstract
If a method for developing organic polymer/apatite core–shell microspheres encapsulating organic polymer microspheres with apatite shells can be constructed, it is possible to establish a fundamental methodology to fabricate apatite capsules for drug delivery carriers. In this study, polystyrene (PS) microspheres were used [...] Read more.
If a method for developing organic polymer/apatite core–shell microspheres encapsulating organic polymer microspheres with apatite shells can be constructed, it is possible to establish a fundamental methodology to fabricate apatite capsules for drug delivery carriers. In this study, polystyrene (PS) microspheres were used as model substances in organic polymer microspheres, and the effects of the surface functional groups on the PS microspheres on the amount of Ca2+ ions introduced onto the PS microspheres were investigated. The PS/apatite core–shell microspheres were prepared by immersing Ca2+-incorporated PS microspheres in a reaction solution containing Ca2+, HPO42−, and Mg2+ to coat the surface of PS microspheres with apatite. Particle characterization of the prepared PS/apatite core–shell microspheres was performed, and the relationships among the surface functional groups, surface potential, Ca2+ adsorption, and apatite shell formation in the aqueous solution on the PS microspheres were investigated. Full article
(This article belongs to the Special Issue Biomedical Composite Applications)
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