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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnosis, Treatment and Prognosis of Head and Neck Cancer
edited by and Elena Russo
submission deadline 20 Jul 2026 | Viewed by 1 | Submission Open
Keywords: head and neck neoplasms; surgical procedures; minimally invasive surgical procedures; radiotherapy; immunotherapy; biomarkers; treatment outcome; early diagnosis; prognosis; quality of life
(This special issue belongs to the Section Oncology)
Clinical Advances in Chronic Lymphocytic Leukemia: Focus on Elderly Frail Patients
edited by Driss Chaoui
submission deadline 20 Jul 2026 | Viewed by 1 | Submission Open
Keywords: CLL; elderly; frailty; guidelines; quality of life; IBTK; BCL2; antiCD20
(This special issue belongs to the Section Hematology)
Minimally Invasive Spine Surgery: Evidence, Advances and Controversies
edited by , Constantine Constantoyannis, Mark A. MacLean and Oliver Lasry
submission deadline 20 Jul 2026 | Submission Open
Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality
(This special issue belongs to the Section Clinical Neurology)
Pneumonia: From Diagnosis to Treatment submission deadline 20 Jul 2026 | Submission Open
Keywords: pneumonia; diagnosis; treatment; multidisciplinary care; pulmonary rehabilitation
(This special issue belongs to the Section Respiratory Medicine)
Clinical Outcomes in Lumbar Spinal Stenosis Treatment
edited by Rafał Staszkiewicz and
submission deadline 20 Jul 2026 | Submission Open
Keywords: lumbar spinal stenosis; clinical outcomes; decompression surgery; conservative management; molecular biomarkers; inflammation and fibrosis; neurotrophic factors; personalized medicine; siganling pathways; quality of life
(This special issue belongs to the Section Orthopedics)
Updates on Reconstructive Urology
edited by
submission deadline 20 Jul 2026 | Submission Open
Keywords: reconstructive urology; urethral stenosis; urethroplasty; urethral diverticulum; ureteral stenosis; male incontinence; urinary diversion; hypospadias; microsurgery; experimental microsurgery; bladder diverticulum; neobladder
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances in Spinal Neurosurgery
edited by Jang-Won Yoon
submission deadline 25 Jul 2026 | 2 articles | Viewed by 1654 | Submission Open
Keywords: minimally invasive spine surgery; lateral lumbar interbody fusion; endoscopic spine surgery; patient-reported out-comes; functional assessment; perioperative care; surgical decision-making
(This special issue belongs to the Section Clinical Neurology)
High-Risk Pregnancy Management: From Prenatal Care to Postpartum Outcomes
edited by Angela Vinturache
submission deadline 25 Jul 2026 | Viewed by 32 | Submission Open
Keywords: high-risk pregnancy; prenatal care; postpartum outcomes; postpartum mental health; birth trauma; AI in obstetrics; medico-legal liability; equity & culturally safe care; indigenous and rural/remote care; EMR-enabled decision support; quality trend monitoring; maternal morbidity and mortality; perinatal morbidity; standardized care bundles & pathways
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Advances and Future Perspectives in Cardiac Arrest and Cardiogenic Shock
edited by Giulia Maj
submission deadline 25 Jul 2026 | Viewed by 18 | Submission Open
Keywords: cardiogenic shock; left ventricular unloading; biomarkers; recovery; cardiac arrest
(This special issue belongs to the Section Emergency Medicine)
Recent Advance in Bariatric Surgery submission deadline 25 Jul 2026 | Viewed by 11 | Submission Open
Keywords: bariatric surgery; metabolic surgery; minimally invasive surgery; robotic surgery; endoscopic bariatric procedures; obesity management; type 2 diabetes remission; perioperative care; long-term outcomes; enhanced recovery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Sleep Disorders: Current Research and Future Directions—Second Edition
edited by Martina Vendrame
submission deadline 25 Jul 2026 | Viewed by 6 | Submission Open
Keywords: obstructive sleep apnea; parasomnia; idiopathic hypersomnia; periodic limb movement disorder; periodic limb move-ment of sleep
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates on Transcatheter Structural Heart Disease Interventions
edited by Nazan Puluca and Hendrik Ruge
submission deadline 25 Jul 2026 | Viewed by 3 | Submission Open
Keywords: interventional valve therapy; TAVR; TEER; TMVR; mitral valve; tricuspid valve; coronary access
(This special issue belongs to the Section Cardiology)
Interaction Between Systemic Diseases and Oral Diseases: 2nd Edition
edited by
submission deadline 25 Jul 2026 | Viewed by 2 | Submission Open
Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Application of Endoscopic Submucosal Dissection in Malignant Gastrointestinal Tumors and Precursors—2nd Edition submission deadline 25 Jul 2026 | Viewed by 1 | Submission Open
Keywords: endoscopy; endoscopic submucosal dissection; endoscopic surgery; laparoscopic surgery; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Updates in the Diagnosis, Imaging, and Treatment of Retinal and Macular Diseases
edited by
submission deadline 26 Jul 2026 | Viewed by 18 | Submission Open
Keywords: retinal diseases; macular degeneration; diagnostic imaging; OCT/OCTA; artificial intelligence; deep learning; clinical ophthalmology; gene therapy; treatment innovations
(This special issue belongs to the Section Ophthalmology)
Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life
edited by and Shaye Kivity
submission deadline 30 Jul 2026 | Viewed by 54 | Submission Open
Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
The Future Direction of Medical Imaging in Hepato-Bilio-Pancreatic Oncology: Challenges and Opportunities
edited by
submission deadline 31 Jul 2026 | Viewed by 4 | Submission Open
Keywords: MRI; CT; molecular imaging; radiomics; imaging; radiogenomics; precision medicine; outcome prediction; cholangiocarcinoma; pancreatic cancer; imaging biomarkers; treatment response
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Neurovascular Canvas: From Basic Science to Clinical Breakthroughs
edited by , Nicola Giannini and
submission deadline 15 Aug 2026 | Viewed by 37 | Submission Open
Keywords: neurovascular unit (NVU); neurodegeneration; vascular biology; stroke; disease modeling
(This special issue belongs to the Section Clinical Neurology)
Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 42 | Submission Open
Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI
(This special issue belongs to the Section Cardiovascular Medicine)
New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches
edited by Gabriella Teresa Capolupo
submission deadline 20 Aug 2026 | Submission Open
Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Dental Care: Oral and Systemic Disease Prevention: 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1221 | Submission Open
Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications
edited by , Tilo Kölbel and José Ignacio F. Torrealba
submission deadline 20 Jul 2027 | Viewed by 93 | Submission Open
Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes
(This special issue belongs to the Section Vascular Medicine)
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