The Role of Inflammation in COVID-19: From Pathophysiology to Treatment.

Dear Colleagues,

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing coronavirus disease – 19 (COVID-19) has introduced a great pandemic in the 2020. A striking need for understanding of COVID-19 pathophysiology and development of efficient treatment strategies is more than evident. The role of inflammation in COVID-19 has soon been recognized. The so-called “cytokine-storm”, whilst a matter of debate, has driven a significant portion of research to strategies focusing on the potential of anti-inflammatory treatment.

The previous months have undoubtedly changed priorities in clinical practice and both bench and bedside research. A wide range of data became available, while a significant amount of studies is ongoing and will probably change the to-date comprehension of this disease. Indeed, in the context of this pandemic even approaches that just attenuate the physical course of the disease - without literally being a definite treatment - are of significant importance.

The present Special Issue aims to explore pathophysiological, diagnostic and treatment aspects of COVID-19 with special interest in the role of inflammation. We would be honored to have robust contributions from eminent experts on the field in order to update the scientific literature both with original research and review articles on this fascinating topic.

Dr. Dimitrios A. Vrachatis
Dr. Spyridon G. Deftereos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.