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Special Issue "Herpesvirus Infections in the Brain"
Deadline for manuscript submissions: closed (25 August 2019).
Interests: Genetic and immunological basis of severe infectious diseases
In recent years, it has emerged that mutations in genes encoding proteins of innate or cell-intrinsic immunity may underlie rare primary immunodeficiencies in humans. Seminal advances have been made in the identification and functional immunological characterization of novel genetic defects predisposing to severe viral infections with herpesviruses, such as HSV-1, HSV-2, VZV, and HHV6. There is now solid evidence to support a role for these herpesviruses not only in causing meningitis and encephalitis, but also in the development of certain autoimmune and neurodegenerative conditions, such as multiple sclerosis and Alzheimer’s disease. These novel insights have been gained through studies on basic epidemiology, genetics, virology, and immunology on the one hand, and the identification of patients with a rare but severe infectious phenotypes, who may directly benefit from our findings in terms of choosing optimal prophylactic and treatment strategies on the other hand. This Special Issue will focus on medically important herpesviruses and describe the basic virology, immune evasion, and immunology relevant for these viruses to gain knowledge of the pathogenesis of severe viral infections in the central nervous system (CNS) and how this knowledge may be used to improve diagnosis, prophylaxis, and treatment of patients.
Prof. Dr. Trine Mogensen
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Innate immunology
- CNS inflammation
- Inborn errors of immunity
- Immune evasion