Recent Advances in Coronary Artery Disease

Dear Colleagues,

Over the course of the recent decades, the mortality rate of coronary artery disease (CAD) has been decreasing due to improvement in the acute coronary syndrome setting. Additionally, our understanding of CAD has been constantly increasing. In particular, new tools and indices able to discern the physiological significance of epicardial coronary stenoses and the function of microcirculation are improving the indication for revascularization and medical therapy. In parallel, non-invasive alternatives are being developed to allow less invasive and more widely applicable diagnoses. The development of new interventional devices and techniques will allow the treatment of anatomically challenging stenosis, such as heavily calcified plaques. In addition, the development of interventional electrophysiology and the frequent coexistence of CAD and arrhythmias are posing management issues but provide potential for combined interventional therapies.

This Special Issue of the Journal of Clinical Medicine will cover the following important aspects of CAD:

• The physiology of coronary flow: from epicardial arteries to microcirculation;
• New methodologies for the assessment of epicardial atherosclerotic lesions;
• New methodologies for the assessment of the microvasculature;
• Novelties in anti-thrombotic therapy;
• Management of patients with CAD and atrial fibrillation;
• New technologies for the treatment of calcified coronary stenoses;
• Novelties in myocardial ischemia assessment;
• New tools for patient risk stratification.

Dr. Emanuele Barbato
Guest Editor

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