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New Frontiers in Endodontic Dentistry
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New Frontiers in Endodontic Dentistry

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 15 August 2024 | Viewed by 6847

Special Issue Editor

Dr. Luciano Giardino

E-Mail Website
Guest Editor
Independent Researcher, 88900 Crotone, Italy
Interests: endodontic diseases; endodontic irrigants; histopathology; implant preservation; oral biofilm; periodontal regeneration; root canal shaping and cleaning; root canal anatomy; endoperiodontal-lesions
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue, "New Frontiers in Endodontic Dentistry", aims to bring together articles covering relevant scientific topics on endodontics and recent advances in the development and optimization of all branches of endodontics such as instrumentation; endodontic anatomy; root canal cleaning systems; biomaterials; the use of tools such as CLSM, MicroCT, etc.; cytotoxicity; the endodontic microbiome; antimicrobials; and irrigants. Therefore, this Special Issue welcomes contributions from all researchers working in dentistry, biomolecular sciences, or material processing in relation to endodontics, regenerative endodontics, and dental restoration. This Special Issue will be a timely approach to survey the recent progress in the development and optimization of these subjects.

Dr. Luciano Giardino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial agents
  • biofilm
  • confocal laser scanning microscopy
  • endodontic materials
  • irrigants
  • microbiome
  • Micro-CT
  • regenerative endodontics
  • sealers
  • sonic and ultrasound endo-treatments

Published Papers (4 papers)

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Research

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12 pages, 1150 KiB  
Article
Extrusion of Sodium Hypochlorite in Oval-Shaped Canals: A Comparative Study of the Potential of Four Final Agitation Approaches Employing Agarose-Embedded Mandibular First Premolars
by Aalisha Parkar, Kulvinder Singh Banga, Ajinkya M. Pawar and Alexander Maniangat Luke
J. Clin. Med. 2024, 13(10), 2748; https://doi.org/10.3390/jcm13102748 - 7 May 2024
Viewed by 305
Abstract
Background: The aim of this investigation was to assess the apical extrusion potential of sodium hypochlorite (NaOCl) in agarose-embedded mandibular first premolars employing four final agitation procedures. Methods: Based on CBCT confirmation of single oval-shaped canals, one hundred extracted mandibular first premolars were [...] Read more.
Background: The aim of this investigation was to assess the apical extrusion potential of sodium hypochlorite (NaOCl) in agarose-embedded mandibular first premolars employing four final agitation procedures. Methods: Based on CBCT confirmation of single oval-shaped canals, one hundred extracted mandibular first premolars were chosen. Using 5.25% NaOCl, the teeth were prepared using the XP Endo Shaper and divided into experimental and control groups. The following were the experimental groups: Group 1 comprised the XP-Endo Finisher, Group 2 the Ultrasonic Activation, Group 3 the Gentle File Finisher Brush, and Group 4 the 27-gauge side-vented needle. To test extrusion, the teeth were placed in a 0.2% agarose gel that contained the pH-sensitive dye m-cresol purple, allowing pixel quantification via ImageJ software (version 1.54i). Results: The XP Endo Finisher featured the most pixels, depicting higher apical extrusion (p < 0.01), followed by the side-vented needle, Gentle File Finisher Brush, and PUI, while the Control Group endured no extrusion. Conclusions: The effective irrigation method for root canal therapy is critical, especially in situations of open apices, resorption, or perforation. According to in vitro experiments, the XP-Endo Finisher has the maximum sodium hypochlorite extrusion, which is determined by parameters such as apical preparation size and irrigation system. Full article
(This article belongs to the Special Issue New Frontiers in Endodontic Dentistry)
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14 pages, 601 KiB  
Article
Post-Operative Quality of Life after Single-Visit Root Canal Treatment Employing Three Different Instrumentation Techniques—An Institutional Randomized Clinical Trial
by Vathsalya Shetty, Shalini Yelke, Dian Agustin Wahjuningrum, Alexander Maniangat Luke, Luca Testarelli, Luciano Giardino and Ajinkya M. Pawar
J. Clin. Med. 2023, 12(4), 1535; https://doi.org/10.3390/jcm12041535 - 15 Feb 2023
Cited by 1 | Viewed by 1664
Abstract
Root canal treatment (RCT) eliminates damaged pulpal tissue and protects the tooth from recurrent microbial invasion. Post-endodontic pain (PEP) is a frequently encountered complication of root canal therapy. It can have an impact on patients’ quality of life (QoL) and their subjective perception [...] Read more.
Root canal treatment (RCT) eliminates damaged pulpal tissue and protects the tooth from recurrent microbial invasion. Post-endodontic pain (PEP) is a frequently encountered complication of root canal therapy. It can have an impact on patients’ quality of life (QoL) and their subjective perception of treatment options. Thus, a self-assessment questionnaire was used to evaluate and compare the influence of manual, rotary, and reciprocating file shaping procedures on immediate post-operative quality of life (POQoL) involving single-visit root canal therapy. It was a double-blinded, randomized, controlled clinical trial. A total of 120 participants were randomly assigned sequentially to three groups comprising 40 patients in each group: Group A: Hand K file (positive control); Group B: ProTaper Next file system; and Group C: WaveOne Gold. Post-operative pain was evaluated using a 4-point visual analog scale (VAS) after 12 h, 24 h, 48 h, 72 h, and 1 week. The highest post-operative pain was with manual instrumentation using hand K files, and the lowest was with reciprocating and rotating instrumentations. No significant difference was noted between the parameters of quality of life assessed, suggesting the filing system or technique had a similar effect. Full article
(This article belongs to the Special Issue New Frontiers in Endodontic Dentistry)
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19 pages, 3117 KiB  
Systematic Review
Cyclic Fatigue Resistance of Rotary versus Reciprocating Endodontic Files: A Systematic Review and Meta-Analysis
by Ana De Pedro-Muñoz, Cristina Rico-Romano, Patricia Sánchez-Llobet, José María Montiel-Company and Jesús Mena-Álvarez
J. Clin. Med. 2024, 13(3), 882; https://doi.org/10.3390/jcm13030882 - 2 Feb 2024
Cited by 1 | Viewed by 951
Abstract
(1) Background: The failure of nickel–titanium (NiTi) rotary files is a complication related to endodontic instruments. The aim of this study was to compare the resistance to cyclic fatigue between rotary and reciprocating file systems. (2) Methods: Specific PICO: Population (P): [...] Read more.
(1) Background: The failure of nickel–titanium (NiTi) rotary files is a complication related to endodontic instruments. The aim of this study was to compare the resistance to cyclic fatigue between rotary and reciprocating file systems. (2) Methods: Specific PICO: Population (P): artificial root canals; Interventions (I): instrumentation with NiTi rotary and reciprocating files; Comparison (C): rotary versus reciprocating files; Outcome (O): cyclic fatigue resistance. Studies were identified through bibliographic research using electronic databases (Medline, Embase, Scopus, SciELO, and WOS). The studies were combined using a random effects model by the inverse variance method. The effect size was the mean of the time to fracture (TTF) and number of cycles to fracture (NCF). Heterogeneity was assessed using the p value of the Q test for heterogeneity and the I2. (3) Results: TTF for rotary files was determined in 474.5 s and 839.1 for reciprocating without statistically significant differences. NCF for rotary systems was determined in 1444.2 and for reciprocating file systems in 4155.9 with statistically significant differences (p = 0.035), making reciprocating files more resistant. (4) Conclusions: Reciprocating files have better resistance to cyclic fatigue than rotary files. When tested in double curvature canals, reciprocating files also showed higher resistance. Full article
(This article belongs to the Special Issue New Frontiers in Endodontic Dentistry)
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10 pages, 2325 KiB  
Case Report
Intentional Replantation as a Starting Approach for a Multidisciplinary Treatment of a Mandibular Second Molar: A Case Report
by João Miguel Santos, Joana A. Marques, Margarida Esteves, Vítor Sousa, Paulo J. Palma and Sérgio Matos
J. Clin. Med. 2022, 11(17), 5111; https://doi.org/10.3390/jcm11175111 - 30 Aug 2022
Cited by 7 | Viewed by 3086
Abstract
Intentional replantation (IR) may offer a solution for persistent periapical lesions associated with endodontically treated teeth. A 35-year-old male patient presented with pain associated with the left mandibular second molar and hypoesthesia. Upon clinical examination, increased probing pocket depth in the mid-buccal surface [...] Read more.
Intentional replantation (IR) may offer a solution for persistent periapical lesions associated with endodontically treated teeth. A 35-year-old male patient presented with pain associated with the left mandibular second molar and hypoesthesia. Upon clinical examination, increased probing pocket depth in the mid-buccal surface was detected. Cone beam computed tomography revealed a previous non-surgical root canal treatment, with root canal filling material extrusion adjacent to the inferior alveolar nerve, a fractured instrument in the mesial root, and a large periapical radiolucency involving both teeth 37 and 36. A diagnosis of symptomatic post-treatment apical periodontitis was established. After discussing treatment options with the patient, an IR of tooth 37 was performed. Extra-oral procedures were completed in 17 min. At 9 months, hypoesthesia resolution was reported, and apical healing was radiographically observed. After 2.5 years, the replanted tooth showed extensive root resorption. An extraction with alveolar ridge preservation, using leukocyte-platelet rich fibrin (L-PRF), was performed. Six months after tooth extraction and regeneration, implant placement surgery was carried out. IR presents a valid treatment modality for the management of post-treatment apical periodontitis. When orthograde retreatment or apical microsurgery prove to be unfeasible, IR is a unique procedure with the potential to promote tooth preservation in properly selected cases. Although unsuccessful after 2.5 years, the IR of tooth 37 allowed for bone regeneration, the maintenance of tooth 36 vitality, and hypoesthesia resolution. Full article
(This article belongs to the Special Issue New Frontiers in Endodontic Dentistry)
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