Special Issue "New Diagnostic and Therapeutic Approaches for the Care of the Severely Injured Patient"
Deadline for manuscript submissions: closed (30 June 2020).
A printed edition of this Special Issue is available here.
Interests: (poly)trauma; risk prediction; treatment strategies; posttraumatic inflammation; genetic polymorphisms
Trauma represents a leading cause of death particularly in the younger population. Traumatic brain injury and hemorrhage are the most common causes of early death, whereas complications such as infections, (multi-)organ failure and “persistent inflammation, immunosuppression, and catabolism syndrome” (PICS) represent relevant factors for late adverse outcome. Pre- and intrahospital diagnostic and therapeutic standard operating procedures have been shown to beneficially influence posttraumatic outcome. However, development of patient-specific diagnostic and therapeutic strategies remains challenging due to uncertainties regarding the assessment of the individual risk profile. Furthermore, the relevance of prevention and rehabilitation measures to avoid unfavorable long-term consequences of trauma is not fully elucidated.
For this Special Issue, we would like to invite authors to submit clinical studies that focus on new diagnostic and therapeutic approaches for the care of the severely injured patient from the preclinical setting to rehabilitation. This includes but is not limited to studies investigating the relevance of biomarkers (e.g., cytokines, extracellular vesicles) as new diagnostic tools, presenting scoring systems for risk assessment, optimizing diagnostic procedures or introducing innovative treatment options. Furthermore, clinical studies that concentrate on the presentation of new prevention and rehabilitation measures or investigate trauma-related factors affecting long-term outcome are of major interest.
Prof. Dr. Frank Hildebrand
Dr. Klemens Horst
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Multiple trauma
- Diagnostic and therapeutic strategy
- Risk prediction
- (Long-term) outcome