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Pediatric Sleep-Disordered Breathing
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Pediatric Sleep-Disordered Breathing

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Pediatrics".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 633

Special Issue Editor

Dr. Audrey Yoon

E-Mail Website
Guest Editor
Sleep Medicine Division, Department of Psychiatry and Behavioral Science, School of Medicine, Stanford University, Stanford, CA 94305, USA
Interests: sleep-disordered breathing; growth modification; surgical orthodontics; orthodontic intervention; pediatric obstructive sleep apnea; miniscrew-assisted palatal expansion; dental sleep medicine

Special Issue Information

Dear Colleagues,

Sleep-disordered breathing (SDB) in children is increasingly recognized as a significant public health concern due to its potential impact on physical, cognitive, and emotional development. Pediatric SDB often arises from multifactorial causes, such as craniofacial anomalies, adenotonsillar hypertrophy, and environmental exposure, making its management complex and multidisciplinary. This Special Issue will focus on the latest advancements in the diagnosis, treatment, and prevention of pediatric SDB. Topics of interest include innovative diagnostic tools, approaches for modifying craniofacial growth and development, behavioral and environmental interventions, and surgical procedures such as adenotonsillectomy or maxillomandibular advancements. Additionally, we aim to explore the role of craniofacial development, orthodontic and dental contributions, and the impact of early interventions on long-term outcomes. This Special Issue will feature original research, reviews, and case studies to provide a comprehensive understanding of pediatric SDB and encourage collaboration across specialties. By addressing this critical area of pediatric health, this Special Issue seeks to promote awareness, inspire innovative treatment approaches, and ultimately improve the quality of life for affected children and their families.

Dr. Audrey Yoon
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric sleep-disordered breathing
  • growth modification
  • pediatric obstructive sleep apnea
  • interdisciplinary management
  • craniofacial development
  • obstructive sleep disorders
  • cognitive behavioral sleep medicine
  • pediatric dental sleep medicine
  • pediatric sleep surgery

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Published Papers (1 paper)

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Research

12 pages, 239 KiB  
Article
Cross-Cultural Adaptation of a Health-Related Quality-of-Life Questionnaire for Children with Obstructive Sleep Disorders: Spanish Version of the OSD-6
by Ignacio Boira, José Norberto Sancho-Chust, Violeta Esteban, Esther Pastor, Miguel Ángel Martínez-García and Eusebi Chiner
J. Clin. Med. 2025, 14(5), 1709; https://doi.org/10.3390/jcm14051709 - 3 Mar 2025
Viewed by 485
Abstract
Background/Objectives: To translate the OSD-6 questionnaire (6-item quality of life questionnaire for children with obstructive sleep disorders) into Spanish and to assess its psychometric properties and clinical usefulness. Methods: We included children with obstructive sleep apnea (OSA). All underwent polysomnography before and after [...] Read more.
Background/Objectives: To translate the OSD-6 questionnaire (6-item quality of life questionnaire for children with obstructive sleep disorders) into Spanish and to assess its psychometric properties and clinical usefulness. Methods: We included children with obstructive sleep apnea (OSA). All underwent polysomnography before and after adenotonsillectomy. Study variables included age, sex, symptoms, polysomnography values, body measurements, and Mallampati and Brodsky classification. Parents or caregivers completed the OSD-6 at baseline and 3 to 6 months after adenotonsillectomy. Following translation and back-translation of the instrument, we evaluated its internal consistency, reliability, construct validity, concurrent validity, predictive validity, and sensitivity to change. Results: We included 45 boys and 15 girls. Mean body mass index was 18 (standard deviation [SD] 4) kg/m2 and mean neck circumference was 28 (SD 5) cm. Seven per cent of children had Brodsky grade 0, 12% had grade 1, 27% had grade 2, 45% had grade 3, and 6% had grade 4. Mean apnea-hypopnea index (AHI) was 12 (SD 7) h−1 before adenotonsillectomy. The overall Cronbach’s alpha was 0.8. We found significant concurrent validity in each questionnaire domain and in the overall score. Predictive validity was significant for Mallampati scores (ANOVA p = 0.011) and borderline significant for AHI levels (ANOVA p = 0.069). The study demonstrated excellent sensitivity to change, both in terms of the overall analysis (p < 0.001) and in each domain (p < 0.001). Moreover, the test-retest reliability was found to be equally excellent (global intraclass correlation coefficient = 0.92 [0.89–0.95]). Conclusions: OSD-6 is a valid and reliable instrument to measure quality of life in children with OSA and can be used in Spanish-speaking countries. Full article
(This article belongs to the Special Issue Pediatric Sleep-Disordered Breathing)
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