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Recent Advances in Diagnosis and Treatment of Vestibular Disorders—2nd Edition
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Recent Advances in Diagnosis and Treatment of Vestibular Disorders—2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 25 June 2025 | Viewed by 2309

Special Issue Editors

Prof. Dr. Angel Ramos-Macias

E-Mail Website
Guest Editor
Department of Otolaryngology, Head and Neck Surgery, Complejo Hospitalario Universitario Insular Materno Infantil de Gran Canaria, 35016 Las Palmas, Spain
Interests: oto-neurology; Ménière’s disease; BPPV; dizziness; cochlear implant; skull base
Special Issues, Collections and Topics in MDPI journals
Dr. Nicolas Perez-Fernandez

E-Mail Website
Guest Editor
Department of Otorhinolaryngology, Clinica Universidad de Navarra, Madrid, Spain
Interests: otoneurology; Ménière’s disease; BPPV; vestibulo-ocular reflex; dizziness; posturography; otopathology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is the second edition of “Recent Advances in Diagnosis and Treatment of Vestibular Disorders” (https://www.mdpi.com/journal/jcm/special_issues/Vestibular_Disorders).

Vestibular medicine centers around the assessment, diagnosis, and treatment of patients with dizziness and vertigo, and, in all these fields, there has been an enormous expansion of research in recent years, the best of which we seek to collate in this Special Issue.

Treatment is now, on occasion, possible for specific diseases, but always by keeping in mind the natural history of the disorder. New methods of treatment, frequently administered at tertiary referral centers, include both common drugs and uncommon medications that have been demonstrated to be applicable to these types of disorder. Gene therapy appears to be possible thanks to the enormous efforts of the genetic mapping of some diseases. On the other hand, surgery, requiring precise anatomical knowledge, being applicable for disabling and unresponsive forms of disease, with new vestibular implants representing a way to solve the most disabling situations when both vestibular systems are nonfunctional. Vestibular rehabilitation by means of sensory substitution, adaptation, and habituation is based on the reweighting of the different sensory systems that allow for dynamic and static equilibrium.

Topics that are welcome in this Special Issue include, but are not limited to, the epidemiology of dizziness, the role of genetics in the development of vestibulopathy, diagnostic approaches, and interventions for patients with dizziness and vertigo, such as medical treatment, surgery, and vestibular rehabilitation.

Prof. Dr. Angel Ramos-Macias
Dr. Nicolas Perez-Fernandez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dizziness
  • vertigo
  • vestibulo-ocular reflex
  • Méniere’s disease
  • nystagmus
  • positional vertigo
  • vestibular implant

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Related Special Issue

Published Papers (2 papers)

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Research

10 pages, 649 KiB  
Article
Association of Tinnitus with Benign Paroxysmal Positional Vertigo
by Hwa Sung Rim, Rugyeom Lee, In-Hwan Oh, Seung Geun Yeo and Sang Hoon Kim
J. Clin. Med. 2025, 14(7), 2473; https://doi.org/10.3390/jcm14072473 - 4 Apr 2025
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Abstract
Background/Objectives: The purpose of this study is to investigate the potential association between tinnitus and benign paroxysmal positional vertigo (BPPV) using large-scale population data to assess the risk of developing one condition in patients who have the other condition. Methods: Using [...] Read more.
Background/Objectives: The purpose of this study is to investigate the potential association between tinnitus and benign paroxysmal positional vertigo (BPPV) using large-scale population data to assess the risk of developing one condition in patients who have the other condition. Methods: Using claims data from the National Health Insurance Corporation spanning 2008 to 2021, we conducted a comprehensive analysis to estimate the risk of developing BPPV in patients with tinnitus and vice versa. This study involved 580,531 patients with tinnitus, 572,937 patients with benign paroxysmal positional vertigo, and their corresponding controls. We used propensity score matching and statistical analyses, including Cox proportional hazard models to assess the association between these conditions. Results: The incidence of BPPV in patients with tinnitus was significantly higher (12.3 per 1000 individuals per year) than that of controls (5.1 per 1000 individuals per year), with an adjusted hazard ratio of 2.474. Additionally, the incidence of tinnitus was significantly higher in patients with BPPV (11.7 per 1000 individuals per year) than in controls (5.5 per 1000 individuals per year), with an adjusted hazard ratio of 2.048. Subgroup analysis showed the risk of developing BPPV in people with tinnitus, and vice versa, was higher in young vs. old people (<39 years) and in men vs. women (p<0.0001). These findings remained significant even after adjusting for sex, age, medical benefits, disability, and health habits. Conclusions: This study provides substantial evidence for a bidirectional association between tinnitus and benign paroxysmal positional vertigo, suggesting an interconnected pathophysiology. Further research is warranted to understand the underlying mechanisms. Full article
(This article belongs to the Special Issue Recent Advances in Diagnosis and Treatment of Vestibular Disorders—2nd Edition)
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12 pages, 1631 KiB  
Article
Limits of Stability during a Therapeutic Exercise Intervention for Instability: Progression, Responders’ and Non-Responders’ Analysis and Predictors
by Laura Flix-Díez, Melissa Blanco-Pareja and Nicolás Pérez-Fernández
J. Clin. Med. 2024, 13(17), 5036; https://doi.org/10.3390/jcm13175036 - 25 Aug 2024
Cited by 1 | Viewed by 1237
Abstract
Background/Objectives: Instability is one of the main symptoms in patients with vestibular and neurological disorders and therapeutic exercise interventions are increasing in popularity as a form of treatment. Additionally, the limits of stability measurement are known to be a good tool for [...] Read more.
Background/Objectives: Instability is one of the main symptoms in patients with vestibular and neurological disorders and therapeutic exercise interventions are increasing in popularity as a form of treatment. Additionally, the limits of stability measurement are known to be a good tool for balance evaluation and monitoring of these interventions. The aim of this work is to better understand how a specific protocol provokes changes on this variable and to study the characteristics of those who do and do not respond to it. Methods: A retrospective study was developed with the data of 40 patients treated in the Otorhinolaryngology department in Clínica Universidad de Navarra (Madrid, Spain). They had an initial reduction in limits of stability, completed the proposed protocol with home-based and hospital-based exercises and with frequent limits of stability remeasurement, and were assisted to a follow-up retest after 1–2 months. Results: A progressive improvement in limits of stability measure was developed through the intervention and was partially retained at follow-up visit. Several differences were found between those patients who improved with the treatment (responders) and those who did not improve (non-responders). More specifically an initial measure of the limits of stability was able to differentiate those groups with a cut-off data of 56 cm2. Conclusions: The proposed protocol was able to induce motor learning in patients included in this study with good retention after 1–2 months. Furthermore, there is some variability in how patients respond to the treatment. Age and diagnosis should be considered and an interesting cut-off data for clinal decision making was found. Full article
(This article belongs to the Special Issue Recent Advances in Diagnosis and Treatment of Vestibular Disorders—2nd Edition)
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