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Updates in Diagnosis and Management of Acute Coronary Syndrome

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (25 December 2024) | Viewed by 1577

Special Issue Editor


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Guest Editor
1. Department of Public Health and Clinical Medicine, Umeå University and Heart Centre, Umeå, Sweden
2. Clinic of Cardiology, University Clinical Centre of Kosova, Rrethi i Spitalit, P.N., 10000 Prishtina, Kosovo
Interests: hypertension; heart failure; insulin resistance; atherosclerosis; diabetes; echocardiography; clinical cardiology; atrial fibrillation; myocardial infarction; blood pressure; cardiovascular medicine; cardiac function; ultrasound imaging; cardiology; electrocardiography; cardiomyopathies; interventional cardiology; diabetes mellitus; cardiac imaging; cardiac echocardiography; coronary angiography; cardiac catheterization; doppler echocardiography; aortic valve; heart rate; ECG; experimental medicine; invasive cardiology

Special Issue Information

Dear Colleagues,

Acute coronary syndrome (ACS) is global health problem that is associated with high rates of mortality and disability. Despite significant investments in its diagnosis and early treatment, including the use of invasive procedures, ACS-related mortality remains high, even in developed countries. Many factors influence ACS-related mortality, including cardiovascular risk factors, clinical presentation and the type of treatment patients receive. Another important factor encompasses the significant difficulties associated with the availability of low-income and free health services in developing countries, which compromise routine procedures and the evidence-based treatment of ACS. This results in significant differences in ASC-related mortality between countries. Studies have also revealed differences in the clinical outcomes of these patients, with the most important predictors of mortality being older age, female gender, renal failure, high blood pressure, severe heart failure, previous CABG, and a reduced left ventricular ejection fraction.

This Special Issue focuses on recent advances in the diagnosis, management, and treatment of patients with ACS. We aim to provide an overview of all diagnostic and treatment modalities already available, in addition to future innovations.

Prof. Dr. Gani Bajraktari
Guest Editor

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Keywords

  • acute coronary syndrome
  • diagnosis
  • primary PCI
  • outcome
  • mortality

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Published Papers (1 paper)

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Research

16 pages, 662 KiB  
Article
RURUS SURYAWAN Score: A Novel Scoring System to Predict 30-Day Mortality for Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
by I Gde Rurus Suryawan, Yudi Her Oktaviono, Budi Baktijasa Dharmadjati, Aldhi Pradana Hernugrahanto, Mochamad Yusuf Alsagaff, David Nugraha, Made Edgard Rurus Surya Erlangga, Pandit Bagus Tri Saputra and Ricardo Adrian Nugraha
J. Clin. Med. 2025, 14(5), 1716; https://doi.org/10.3390/jcm14051716 - 4 Mar 2025
Viewed by 470
Abstract
Background/Objectives: It is essential to identify acute myocardial infarction patients with greater risk of deterioration following primary percutaneous coronary intervention. Due to an inconsistent result about predictors of 30-day outcomes regarding scoring systems for the first episode of acute myocardial infarction, the [...] Read more.
Background/Objectives: It is essential to identify acute myocardial infarction patients with greater risk of deterioration following primary percutaneous coronary intervention. Due to an inconsistent result about predictors of 30-day outcomes regarding scoring systems for the first episode of acute myocardial infarction, the objective of this study is to develop novel scoring systems to predict 30-day mortality among patients with a first episode of acute myocardial infarction who underwent primary percutaneous coronary intervention. Methods: This retrospective study was conducted with total sampling for all patients with first-time acute myocardial infarction who underwent primary percutaneous coronary intervention between 2021 and 2024 at Dr. Soetomo Hospital, Indonesia. We performed a total sampling and collected 1714 patients, of which 1535 patients were included. Our primary outcomes included 30-day mortality. Results: The analysis included 1535 patients: 926 in the derivation set and 609 in the validation set. In our study, the 30-day mortality rate was 20.7%. Multivariate logistic regression analysis was used to build prediction models in the derivation group and then validated in the validation cohort. The area under the ROC curve of the RURUS SURYAWAN score to predict 30-day mortality was 0.944 (0.906–0.972) in the derivation set and 0.959 (0.921–0.983) in the validation set, with 94.6% sensitivity and 97.3% specificity (p < 0.001). Conclusions: After adjusting for potential confounders, we developed RURUS SURYAWAN, a novel scoring system to identify predictors of 30-day mortality among acute myocardial infarction before primary percutaneous coronary intervention. Full article
(This article belongs to the Special Issue Updates in Diagnosis and Management of Acute Coronary Syndrome)
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