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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chronic Obstructive Pulmonary Disease (COPD): From Pathogenesis to Therapy

edited by José M. Marin

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5460 | Submission Open

Keywords: COPD; COPD mechanisms; COPD pathology; COPD pharmacology; cytokine biology; biomarkers; early diagnosis; inflammation; COPD management; new therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pediatric Diseases: From Molecular Mechanisms to Novel Therapeutic Strategies

edited by

Elena Tarca

submission deadline 20 Jul 2025 | 4 articles | Viewed by 5413 | Submission Open

Keywords: congenital abnormalities; genetic disease; molecular mechanism; therapeutic agents; maternal and fetal medicine; pediatric diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Prevention, Diagnosis and Treatment of Pediatric Diseases

edited by

Giovanni Fiorito

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5407 | Submission Open

Keywords: pediatric diseases; bioinformatics; in utero and early-life exposures; multi-omic biomarkers; personalized medicine; diagnosis; prevention

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Beyond Digestion: The Role of Gut Microbiota in Metabolism, Immunity and Brain Function

edited by

Alip Borthakur

submission deadline 20 Jul 2025 | 4 articles | Viewed by 5372 | Submission Open

Keywords: gut dysbiosis; gut microbiota; metabolism

(This special issue belongs to the Section Molecular Immunology)

Genetic Basis of Autism Spectrum Disorder

edited by

Elisabetta Bolognesi

and

Franca Rosa Guerini

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5364 | Submission Open

Keywords: autism spectrum disorder (ASD); neurodevelopmental disorder (NDD); genetic causes of autism; genetic polymorphism; gene variant; genome-wide association studies; single nucleotide; polymorphism; precision medicine; genetic mutations; diagnostic marker

(This special issue belongs to the Section Molecular Genetics and Genomics)

Functional Role of Non-coding RNAs in Cancer: Inside and outside Cells

edited by

Simone Anfossi

and

Linda Fabris

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5323 | Submission Open

Keywords: ncRNAs; gene expression regulation; biological functions; extracellular vesicles; intercellular communication; cancer progression; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Molecular Linkage between Atherosclerosis and Extracellular Vesicles

edited by

Wioletta Olejarz

submission deadline 20 Jul 2025 | 2 articles | Viewed by 5279 | Submission Open

Keywords: atherosclerosis; extracellular vesicles; exosomes; vascular inflammation; stroke; biomarkers; miRNA; stem and progenitor cells; cardiovascular diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Discovery of Microbial and Plant Specialized Metabolites

edited by

Marco Masi

submission deadline 20 Jul 2025 | 4 articles | Viewed by 5272 | Submission Open

Keywords: natural products; specialized metabolites; secondary metabolites; plant; pharmacology

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Glia in Neuropsychiatric Disorders

edited by

Guillaume Lucas

submission deadline 20 Jul 2025 | 2 articles | Viewed by 5261 | Submission Open

Keywords: glial cells; astrocytes; microglia; neuro-inflammation; synaptic plasticity; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Neurobiology)

New Insights into Plant Pathology and Abiotic Stress

edited by

Shoupu He

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5192 | Submission Open

Keywords: plant pathology; abiotic stress; molecular mechanisms; stress resistance; signaling pathways; epigenetics; omics technologies; disease management; climate change; plant stress responses

(This special issue belongs to the Section Molecular Plant Sciences)

Plasticity of the Nervous System after Injury: 2nd Edition

edited by

Xavier Navarro

and

Tessa Gordon

submission deadline 20 Jul 2025 | 4 articles | Viewed by 5139 | Submission Open

Keywords: neural plasticity; axonal regeneration; nerve injury; glial cells; central nervous system

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Zoology

edited by

Valeria Maselli

submission deadline 20 Jul 2025 | 5 articles | Viewed by 5135 | Submission Open

Keywords: zoology; genomics; transcriptomics; phylogeny; molecular evolution; mtDNA; eDNA; RNA; molecular zoolog

(This special issue belongs to the Section Molecular Biology)

New Insights into Immune Dysregulation Disorders

edited by

Francesco Saettini

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5111 | Submission Open

Keywords: immune dysregulation disorders; autoimmune conditions; primary immunodeficiencies; autoinflammatory disorders

(This special issue belongs to the Section Molecular Immunology)

Inflammatory Signaling Pathways Involved in Gastrointestinal Diseases: Second Edition

edited by

Diana Di Liberto

and

Marianna Lauricella

submission deadline 20 Jul 2025 | 2 articles | Viewed by 5091 | Submission Open

Keywords: inflammatory signaling pathways; gastrointestinal diseases; gastrointestinal cancer; inflammatory bowel disease; colonitis; colorectal cancer; cytokine

(This special issue belongs to the Section Molecular Immunology)

Marine Omics

edited by

Mónica Carrera

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5015 | Submission Open

Keywords: marine; seafood; omics; genomics; proteomics; transcriptomics; metabolomics; systems biology

(This special issue belongs to the Section Biochemistry)

Signaling Pathways and Novel Therapies in Heart Disease

edited by

Anindita Das

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4921 | Submission Open

Keywords: heart failure; arrhythmias; ischemic heart disease; myocardial regeneration; inflammation; gene- or cell-based therapy; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Peroxisome and Lysosome in Health and Disease

edited by

Anne Vejux

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4908 | Submission Open

Keywords: peroxisomes; lysosomes; autophagy; lysosomal diseases; peroxidase; oxidative stress; acid hydrolase; lysosomal storage disease(LSD); gaucher disease

(This special issue belongs to the Section Molecular Biology)

Advances in Molecular Forensic Pathology and Toxicology: An Update

edited by

Angelo Montana

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4902 | Submission Open

Keywords: biomarkers; immunohistochemistry; histopathology; forensic pathology; forensic toxicology; forensic biomarkers; toxicological biomarkers; neuropathology; mRNA; post-mortem interval; cerebral damage; in vitro; in vivo; and in silico models; hypoxic– ischemic brain injury; pregnancy biomarkers; vitality

(This special issue belongs to the Section Molecular Biology)

NRF2/KEAP1 Signalling in Cancer

edited by

Sonia Fantone

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4781 | Submission Open

Keywords: oxidative stress; cancer; aging; senescence; inflammation; ovarian cancer; prostate cancer; antioxidants

(This special issue belongs to the Section Molecular Biology)

Pathways in Development and Disease: The Role of RNA Regulation in Biological and Pathological Events

edited by

Guilherme Tralhão

and

Rui Caetano Oliveira

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4739 | Submission Open

Keywords: RNA; human disease; cancer; diagnostic; therapy; development

(This special issue belongs to the Section Biochemistry)

Recent Advances in Electrochemical-Related Materials

edited by Celia García-Hernandez

submission deadline 20 Jul 2025 | 4 articles | Viewed by 4725 | Submission Open

Keywords: novel electrochemical devices; advanced micro- and nanomaterials for electrochemical applications; batteries; fuel and photoelectrochemical cells; electrochemical sensors and biosensors; new advances in supercapacitors; electrochemical electrolyzers; advanced electrochemical materials for environmental applications

(This special issue belongs to the Section Materials Science)

Transporters in Health and Disease

edited by

Giuliano Ciarimboli

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4720 | Submission Open

Keywords: transporters; disease; regulation; drugs; toxicity; signaling

(This special issue belongs to the Section Molecular Biology)

Advances, Pitfalls and Future Perspectives for CRISPR/Cas9 Mediated Genome Editing: 4th Edition

edited by

Alexander Kondrashov

and

Timofey S. Rozhdestvensky

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4694 | Submission Open

Keywords: molecular insights into different approaches and methods for CRISPR/Cas9 genome editing; the generation of disease models; the CRISPR/Cas9-mediated genome editing of ES cells; the CRISPR/Cas9 system in cancer biology; CRISPR/Cas9-mediated genome editing in model organisms (plants; fungi and animals); the CRISPR/Cas9 system in epigenetic research; the CRISPR/Cas9 system in gene therapy— applications and the challenges in the implementation of this technology; the CRISPR/Cas9 system beyond genome editing (molecular markers; biosensors; etc.)

(This special issue belongs to the Section Molecular Biology)

Vegetable Genetics and Genomics, 3rd Edition

edited by

Yunsong Lai

and

Xixiang Li

submission deadline 20 Jul 2025 | 4 articles | Viewed by 4636 | Submission Open

Keywords: major vegetable crops; genome; variome; genotyping; GWAS; QTL mapping; functional genome; metabolome; breeding target characters; genetic mechanism; functional genes

(This special issue belongs to the Section Molecular Plant Sciences)

Integrative Multi-Omics Analysis for Cancer Biomarkers

edited by

Youping Deng

and

Kurt K. Zhang

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4619 | Submission Open

Keywords: bioinformatics; biomedical informatics; cancer; genomics; systems biology

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms and Functions of Macrophage Cells

edited by Magdalena Król

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4586 | Submission Open

Keywords: macrophages; immune responses; inflammation; cancer; tumor microenvironment

(This special issue belongs to the Section Molecular Immunology)

Molecular Insights into Zoonotic Diseases

edited by

Vishwanath Venketaraman

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4520 | Submission Open

Keywords: mycobacterial diseases; bubonic and pneumonic plague; Q fever; cat scratch disease; Mediterranean fever; HIV; malaria; ADIS; SARS-CoV-2; adjunctive therapy; immune-enhancing agents; antimycobacterial compounds; host-directed therapies; pathogenesis; modulation of host immune responses

(This special issue belongs to the Section Molecular Microbiology)

Molecular Insight into Alzheimer’s Disease

edited by Thierry Oster and Catherine Malaplate

submission deadline 20 Jul 2025 | 5 articles | Viewed by 4461 | Submission Open

Keywords: Alzheimer’ s disease; cellular and molecular mechanisms; neuronal membranes; endocytosis; and vesicular trafficking; molecular crosstalk between neurons and glial cells; protein interaction with lipids or other proteins; biomarkers and diagnosis; epidemiology; risk factors; and prevention; therapeutic visions

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Biology of Osteoporosis

edited by

Harish K. Datta

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4455 | Submission Open

Keywords: osteoporosis; bone; signalling; molecular; fractures; endocrine; paracrine

(This special issue belongs to the Section Molecular Biology)

Applications of Stem Cells and Extracellular Vesicles in Regenerative Medicine

edited by

Ramya Lakshmi Rajendran

and

Prakash Gangadaran

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4420 | Submission Open

Keywords: regenerative medicine; pluripotent stem cells; cell differentiation; tissue engineering; gene editing; therapeutic potential; clinical applications; neurodegenerative disorders; disease modeling

(This special issue belongs to the Section Molecular Biology)

Non-small Cell Lung Cancer: From Molecular Mechanisms to Therapeutic Strategies

edited by Lorenzo Belluomini

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4381 | Submission Open

Keywords: NSCLC; predictive and prognostic biomarkers; immunotherapy; targeted therapy; special populations

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Human Retrovirus Infection: 2nd Edition

edited by

Yosuke Maeda

Toshio Hattori

and Kotaro Shirakawa

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4374 | Submission Open

Keywords: retrovirus; ATL; HIV-1; AIDS

(This special issue belongs to the Section Molecular Microbiology)

Biomaterials for Drug Delivery and Advanced Therapies

edited by

Annalisa Bianchera

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4338 | Submission Open

Keywords: polymers; biomaterials; drug delivery; scaffold; ATMPs; tissue regeneration

(This special issue belongs to the Section Materials Science)

Advances in Agro-Polymers

edited by

In Chul Um

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4299 | Submission Open

Keywords: cellulose; lignin; starch; fibroin; sericin; keratin; soy; zein; pectin; collagen; biocompatibility; biodegradability

(This special issue belongs to the Section Materials Science)

Antibacterial Activity against Drug-Resistant Strains, 2nd Edition

edited by

Rosa Sessa

and

Simone Filardo

submission deadline 20 Jul 2025 | 4 articles | Viewed by 4242 | Submission Open

Keywords: antibacterial activity; novel antimicrobial agents; drug-resistant strains; molecular mechanisms; emerging drug-resistant pathogens; genetic determinants; impact of MDR pathogens on human health; molecular methods for the diagnosis of antibiotic resistance

(This special issue belongs to the Section Molecular Microbiology)

New Insights into the Immunopathology of Infectious Diseases

edited by Marta Camici

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4189 | Submission Open

Keywords: infection immunology; immune dysregulation in infectious diseases; interactions between infective agents and immune responses; modeling of the immune system; new pathways of pathogenesis

(This special issue belongs to the Section Molecular Immunology)

Molecular Toxicity of Foodstuff Contaminants and Mitigation Strategies

edited by

Lihong Zhao

and Matthew Koci

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4189 | Submission Open

Keywords: antibiotics; heavy metals; pesticides; mycotoxins; foodborne pathogens; polycyclic aromatic hydrocarbons; microplastics; toxicity; biodegradation; detoxification

(This special issue belongs to the Section Molecular Toxicology)

Recent Insights into Colorectal Cancer Treatment

edited by Fee Klupp

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4188 | Submission Open

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms Involved in Sperm Development, Maturation, and Fertilization (3rd Edition)

edited by

Jan Tesarik

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4120 | Submission Open

Keywords: sperm physiology; seminal plasma; extracellular vesicles; reproduction; spermatogenesis; capacitation; fertility

(This special issue belongs to the Section Molecular Biology)

Novel Insights into Regenerative Medicine

edited by

Jorge U. Carmona

and

Marco Tatullo

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4099 | Submission Open

Keywords: regenerative medicine; tissue regeneration; stem cell; platelet-rich plasma; growth factors; cytokines; bioscaffolds; gels

(This special issue belongs to the Section Materials Science)

Molecular Investigations in Neurodevelopmental Disorders

edited by Giorgio Medici

submission deadline 20 Jul 2025 | 4 articles | Viewed by 3972 | Submission Open

Keywords: neurodevelopmental disorders; brain; neurons; synapses; molecular research; regulatory networks; molecular pathways; biomarkers; therapies

(This special issue belongs to the Section Molecular Neurobiology)

The Effect of Food-Derived Compounds on Brown Fat Cell Function

edited by

Nobuyuki Takahashi

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3971 | Submission Open

Keywords: brown adipocyte; beige adipocyte; nutrients; food-derived components; thermogenesis; energy homeostasis; inflammation; obesity; diabetes; insulin resistance; metabolic syndrome; adipokines; lipid and carbohydrate metabolism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Amyloidosis in Pathobiology and Therapy

edited by

Kazufumi Nakamura

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3970 | Submission Open

Keywords: amyloidosis; ATTR; transthyretin; misfolding; molecular mechanisms; molecular therapeutic targets; molecular imaging; SPECT; tracers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Investigating Host-Parasite Interactions for the Discovery of Novel Therapies and Vaccine Targets

edited by

Natalie Nieuwenhuizen

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3860 | Submission Open

Keywords: parasites; host-pathogen interactions; helminths; worms; protozoans; leishmania; malaria; schistosomiasis; trypanosomiasis; ascariasis; anisakiasis; vectors; mosquitoes; ticks; neglected tropical diseases

(This special issue belongs to the Section Molecular Immunology)

Molecular Research in Fruit Crop: Second Edition

edited by

Chen Wang

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3840 | Submission Open

Keywords: fruit crop; biotechnology; hormonal; environmental signals

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Molecular Mechanisms of Neurodegenerative Diseases

edited by Aslihan Ugun-Klusek

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3769 | Submission Open

Keywords: neurodegeneration; Parkinson’ s disease; Alzheimer’ s disease; molecular signalling; neuronal death

(This special issue belongs to the Section Molecular Neurobiology)

Nanoparticles in Inhaled Drug Delivery

edited by

Nazrul Islam

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3757 | Submission Open

Keywords: inhaled nanoparticles; inhaled antibacterial formulations and delivery; inhaled anticancer drugs; polymeric drug nanoparticles for lung delivery; controlled release of inhalable antibacterial/anticancer drugs and their toxicity

(This special issue belongs to the Section Materials Science)

Post-transcriptional and Epigenetic Mechanisms Controlling Stem Cells Differentiation

edited by

Sorina Dinescu

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3741 | Submission Open

Keywords: stem cell differentiation; adipogenesis; neurogenesis; epigenetics; post-transcriptional modification; ncRNAs

(This special issue belongs to the Section Molecular Biology)

From Molecules to Medicines: Exploring Neurodegenerative Pathways for Targeted Neuropharmacology

edited by

Malgorzata Zaremba

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3711 | Submission Open

Keywords: disease modeling; drug studies; therapeutic interventions; neuropharmacology; innovative pharmacological interventions

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Dynamics Simulations and Structural Analysis of Protein Domains (2nd Edition)

edited by

Alexandre G. De Brevern

submission deadline 20 Jul 2025 | 4 articles | Viewed by 3644 | Submission Open

Keywords: protein structures; molecular dynamics; advanced molecular dynamics; variants; pathologies; drug design; allostery; protein domains; secondary structures; methodological development; protein design; ligands; normal mode analysis; machine learning

(This special issue belongs to the Section Molecular Informatics)

Displaying special issue 251-300 on page 6 of 68.

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