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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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State-of-the-Art Molecular Neurobiology in Chile, 2nd Edition

edited by

Juan Orellana

submission deadline 20 Aug 2025 | 4 articles | Viewed by 7798 | Submission Open

Keywords: neurological disorders; neurodegeneration; pharmacology; protein structure; neuroinflammation; neurophysiology

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances in Wound Healing: 2nd Edition

edited by

Alina Maria Holban

and

Carmen Curutiu

submission deadline 20 Aug 2025 | 6 articles | Viewed by 7761 | Submission Open

Keywords: management of wounds; nanobiomaterials; infection control; chronic wounds; biofilm infections; wound dressings; tissue engineering; wound healing

(This special issue belongs to the Section Molecular Biology)

Stress Response Research: Yeast as Models: 2nd Edition

edited by

Cristina Mazzoni

and

Sergio Giannattasio

submission deadline 20 Aug 2025 | 4 articles | Viewed by 7730 | Submission Open

Keywords: yeast; stress response; genetic disease; age-related disease; cell factory

(This special issue belongs to the Section Molecular Biology)

Oxidative Stress and Inflammation in Health and Disease

edited by Fabio Vivarelli and

Donatella Canistro

submission deadline 20 Aug 2025 | 4 articles | Viewed by 7684 | Submission Open

Keywords: oxidative stress; inflammation; chronic diseases; risk factors; prevention

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomolecular Basis of Life Processes

edited by

Janusz Błaszczyk

submission deadline 20 Aug 2025 | 3 articles | Viewed by 7592 | Submission Open

Keywords: energy metabolism; bone-muscle interaction; ATP signalling; calcium– phosphate signalling; metabolic syndrome; aging; cellular turnover; cancers

(This special issue belongs to the Section Molecular Biology)

Mast Cells in Immunity and Disease: Second Edition

edited by

Davide Firinu

Giovanni Paoletti

and

Giulia Costanzo

submission deadline 20 Aug 2025 | 5 articles | Viewed by 7490 | Submission Open

Keywords: mast-cell activation; secretion of MC-derived mediators; allergy; asthma; allergic rhinitis; urticaria; anaphylaxis; mastocytosis

(This special issue belongs to the Section Molecular Immunology)

Pathogenesis and Novel Therapeutic Approaches for Sarcomas

edited by Francisco Giner

submission deadline 20 Aug 2025 | 4 articles | Viewed by 7425 | Submission Open

Keywords: soft tissue tumors; bone tumors; molecular biology; target therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioceramics: Challenges and Medical Applications of Calcium-Phosphate-Based Biocompatible Ceramics

edited by

Kazuaki Hashimoto

and Mamoru Aizawa

submission deadline 20 Aug 2025 | 7 articles | Viewed by 7407 | Submission Open

Keywords: calcium phosphate synthesis; functional biomaterials; biological bone cements and adhesives; surface and interface properties; antibacterial and antiviral material; properties for medical applications; drug delivery properties; therapy and diagnostics; in vitro and in vivo evaluation

(This special issue belongs to the Section Materials Science)

Metabolic Dysfunction-Associated Steatotic Liver Disease: From Basic Research to Clinical Approaches

edited by

Barbara Toffoli

submission deadline 20 Aug 2025 | 4 articles | Viewed by 7395 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); steatosis; obesity; type 2 diabetes mellitus; therapeutic targets and interventions

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Advances in Reproduction Biology

edited by Clara Malo

submission deadline 20 Aug 2025 | 8 articles | Viewed by 7347 | Submission Open

Keywords: gamete formation; fertilization; embryo formation; embryo implantation; fertility; infertility; molecular markers; reproductive biology

(This special issue belongs to the Section Molecular Biology)

Abiotic Stress Tolerance and Genetic Diversity in Plants, 2nd Edition

edited by

Andrés J. Cortés

submission deadline 20 Aug 2025 | 6 articles | Viewed by 6998 | Submission Open

Keywords: biodiversity; molecular breeding; comparative genomics; abiotic stress adaptation; genetic mapping; predictive breeding; genomic prediction; assisted gene flow; plant breeding; restoration ecology; conservation genetics

(This special issue belongs to the Section Molecular Plant Sciences)

Signaling Molecules Involved in Gametes Development, Differentiation and Fertilization, 2nd Edition

edited by

Sergio Minucci

and

Massimo Venditti

submission deadline 20 Aug 2025 | 4 articles | Viewed by 6845 | Submission Open

Keywords: spermatogenesis; oogenesis; spermatozoa; oocyte; fertilization; acrosome reaction; fertility; epidydimal transit; endocrine disrupting chemicals; testicular and ovarian cancer

(This special issue belongs to the Section Molecular Biology)

Toxicity of Heavy Metal Compounds

edited by

Astrid Barkleit

submission deadline 20 Aug 2025 | 5 articles | Viewed by 6786 | Submission Open

Keywords: heavy metal; coordination; complexation; binding form; speciation; biomolecules; (cyto-) toxicity; cell death mechanism; spectroscopy; microscopy

(This special issue belongs to the Section Molecular Toxicology)

Mitochondrial Function in Health and Diseases

edited by Sally P. Wheatley

submission deadline 20 Aug 2025 | 5 articles | Viewed by 6730 | Submission Open

Keywords: mitochondria; metabolism; lipid; ATP; respiration; calcium; iron; inheritance; apoptosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances and Challenges of Molecular Research on Disease in Animal Models in Biomedicine

edited by Minolfa C. Prieto

submission deadline 20 Aug 2025 | 5 articles | Viewed by 6718 | Submission Open

Keywords: animal models; cardiovascular disease; renal disease; metabolic; neurological; behavioral; and oncological disorders; pathophysiology; cell and molecular research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Apolipoproteins and Lipoproteins in Health and Disease, 3rd Edition

edited by

Joan Carles Escolà-Gil

submission deadline 20 Aug 2025 | 5 articles | Viewed by 6698 | Submission Open

Keywords: apolipoproteins; Alzheimer's disease; atherosclerosis; cancer; cholesterol; diabetes; inflammation; obesity; lipid metabolism; lipoproteins

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Breakthroughs in Diagnostic Prediction and Fundamental Therapeutics of Dementia and Movement Disorders, 2nd Edition

edited by

Yasemin M. Akay

submission deadline 20 Aug 2025 | 5 articles | Viewed by 6497 | Submission Open

Keywords: Parkinson's disease; dementia with Lewy bodies; Alzheimer's disease; pathogenic protein; biomarker; therapeutic target; drug

(This special issue belongs to the Section Molecular Neurobiology)

Editorial Board Members’ Collection Series: “Molecular Research in NeuroInflammation”

edited by

Ludmilla Morozova-Roche

Matthew G. Frank

and

Christina Piperi

submission deadline 20 Aug 2025 | 4 articles | Viewed by 6462 | Submission Open

Keywords: neuroinflammation; microglia; astrocytes; immune cells; Alzheimer; Parkinson

(This special issue belongs to the Section Molecular Neurobiology)

New Insights in Translational Bioinformatics: Second Edition

edited by

Camelia Quek

submission deadline 20 Aug 2025 | 3 articles | Viewed by 6460 | Submission Open

Keywords: translational research; sequencing; single cell; spatial biology; treatment; diagnostics; machine learning; artificial intelligence; model; computational biology

(This special issue belongs to the Section Molecular Informatics)

Insights into Chronic Liver Disease and Hepatocellular Carcinoma

edited by Marios Papadakis

submission deadline 20 Aug 2025 | 3 articles | Viewed by 6383 | Submission Open

Keywords: chronic liver disease; hepatocellular carcinoma; tumor microenvironment; viral hepatitis

(This special issue belongs to the Section Molecular Oncology)

Biomarkers, Treatments, and Clinical Outcomes for Meningiomas and Other Skull Base Tumors

edited by

Michael Graner

and Philip David Tatman

submission deadline 20 Aug 2025 | 3 articles | Viewed by 6237 | Submission Open

Keywords: skull base tumor; meningioma; biomarkers; diagnosis; prognosis; radiology; surgery; pharmacotherapy; immunology

(This special issue belongs to the Section Molecular Oncology)

The Roles of Photodynamic Therapy in Tumors and Cancers

edited by Jianyong Liu

submission deadline 20 Aug 2025 | 4 articles | Viewed by 6163 | Submission Open

Keywords: photodynamic therapy; PDT; photodetection; photosensitizers; photosensitizing agents; reactive oxygen species; molecular mechanisms; cell necrosis; apoptosis; singlet oxygen; synergetic therapy; combination therapy; delivery vehicles; immunophototherapy; nano-photosensitizer

(This special issue belongs to the Section Molecular Oncology)

Epilepsy Research and Antiepileptic Drugs, 2nd Edition

edited by

Sonia Mayo

submission deadline 20 Aug 2025 | 2 articles | Viewed by 5969 | Submission Open

Keywords: refractory epilepsy; pharmacoresistant epilepsy; antiepileptic drug; seizure; molecular mechanisms; prognosis; pharmacogenomics

(This special issue belongs to the Section Molecular Pharmacology)

New Molecular Mechanisms in the Development of Brain Tumors and Metastases

edited by

Raffaele Addeo

Michele Caraglia

and

Marianna Abate

submission deadline 20 Aug 2025 | 2 articles | Viewed by 5941 | Submission Open

Keywords: brain tumor; brain metastasis; blood– brain barrier; target therapy; cancer molecular biology; brain tumor microenvironment; molecular biomarkers

(This special issue belongs to the Section Molecular Oncology)

Plant Chloroplasts and Mitochondria: Key Organelles for Sustainable Agriculture

edited by

Nunzia Scotti

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5885 | Submission Open

Keywords: ‘ omics’ ; photosynthesis; energy production; crops; climate change; sustainable agriculture; stress response; inter-organelle crosstalk; signaling networks; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

Fatty Acid Oxidation, Lipid Mediators and Dietary Fatty Acids in the Molecular Mechanisms of Diseases

edited by

Cinzia Signorini

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5692 | Submission Open

Keywords: fatty acid oxidation; inflammation; lipid mediators; lipid metabolism; omega-3 fatty acids; oxidative stress; dietary supplementation; animal models; human diseases

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Role of Hormones and Nutrients in Health and Disease

edited by

Maria Scuto

submission deadline 20 Aug 2025 | 2 articles | Viewed by 5664 | Submission Open

Keywords: sensory nutrients; steroid hormones; oxidative stress; inflammation; Nrf2 pathway; neurodegenerative disorders; psychiatric diseases; personalized nutritional therapy; organoid technology

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advanced Research on the Adrenal Gland and Hormones

edited by Marcin Ruciński

submission deadline 20 Aug 2025 | 3 articles | Viewed by 5567 | Submission Open

Keywords: bioactive peptides; adrenal gland; adrenocortical carcinoma; HPA axis; G protein-coupled receptor; hormones; steroidogenesis

(This special issue belongs to the Section Molecular Pharmacology)

The Characterization and Application of Enzymes in Bioprocesses

edited by Loredana Marcolongo

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5549 | Submission Open

Keywords: biocatalysts; enzymatic characterization; enzymatic action; protein engineering; biocatalysts application; bioprocessing

(This special issue belongs to the Section Biochemistry)

Antioxidants as Regulators of Metabolic Pathways: Potential and Therapeutic Strategies

edited by Halina Tkaczenko and

Natalia Kurhaluk

submission deadline 20 Aug 2025 | 2 articles | Viewed by 5371 | Submission Open

Keywords: antioxidants; metabolic pathways; oxidative stress; cellular homeostasis; redox signaling; energy metabolism; lipid metabolism; therapeutic strategies; chronic diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Research in Gynecological Diseases—2nd Edition

edited by

David B. Alexander

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5337 | Submission Open

Keywords: malignant gynecological diseases; screening for gynecological cancers; benign gynecological conditions; screening for benign gynecological diseases; endometriosis; polycystic ovaries syndrome; ovarian cysts; uterine fibroids; leiomyomas; adenomyosis; pelvic inflammatory disease; vaginitis; vaginal dysbiosis; treatment targets for gynecological diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Using Model Organisms to Study Complex Human Diseases

edited by

Roberto Piergentili

submission deadline 20 Aug 2025 | 5 articles | Viewed by 5290 | Submission Open

Keywords: model organism; Escherichia coli; yeast; Caenorhabditis elegans; Drosophila melanogaster; zebrafish; Arabidopsis thaliana; Xenopus laevis; rat and mouse model; human disease; inherited disease; cancer; rare disease; genetics

(This special issue belongs to the Section Molecular Biology)

Modern Plant Cell Biotechnology: From Genes to Structure, 2nd Edition

edited by

Ewa Kurczyńska

and

Alexander Betekhtin

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5287 | Submission Open

Keywords: genetic engineering techniques; gene modification; gene editing; regulation of gene expression; plant cell biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Ligament/Tendon and Cartilage Tissue Engineering and Reconstruction

edited by

Gundula Schulze-Tanzil

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5287 | Submission Open

Keywords: cartilage; tendon; ligament; anterior cruciate ligament; bioprinting; scaffold; bioreactor; tissue engineering

(This special issue belongs to the Section Molecular Biology)

Machine Learning and Bioinformatics in Human Health and Disease: 2nd Edition

edited by

Andreas Leiherer

submission deadline 20 Aug 2025 | 3 articles | Viewed by 5209 | Submission Open

Keywords: machine learning; bioinformatics; deep learning; multi-omics approaches; genetic risk factors; drug interactions; precision medicine; neurodegenerative diseases; disease diagnosis; epidemic prediction

(This special issue belongs to the Section Molecular Informatics)

Advances in Novel Anti-Alzheimer Drugs: Biological Target, Medicinal Chemistry and Formulation

edited by

Marc Since

and Aurélie Malzert-Fréon

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5148 | Submission Open

Keywords: Alzheimer’ s disease; drug design; amyloid peptide; biological targets; medicinal chemistry; formulation

(This special issue belongs to the Section Molecular Pharmacology)

Mitochondria: Transport of Metabolites Across Biological Membranes

edited by

Graziantonio Lauria

and

Rosita Curcio

submission deadline 20 Aug 2025 | 2 articles | Viewed by 5109 | Submission Open

Keywords: mitochondria; mitochondrial transporters; mitochondrial metabolism; transport proteins; translocases carriers; mitochondrial carriers; mitochondrial diseases; mitochondrial permeability; apoptosis

(This special issue belongs to the Section Molecular Biology)

Role of MicroRNAs in Cancer Development and Treatment, 2nd Edition

edited by

Nikolay Mehterov

submission deadline 20 Aug 2025 | 2 articles | Viewed by 5093 | Submission Open

Keywords: microRNAs (miRNAs); transcriptomics; functional studies; cancer pathobiology; solid tumors; hematological malignancies; molecular biomarkers; therapeutic targets; apoptosis; anticancer drugs radiotherapy; chemotharapy failure

(This special issue belongs to the Section Molecular Oncology)

New Horizons in Silicon Chemistry

edited by Mitsuo Kira

submission deadline 20 Aug 2025 | 3 articles | Viewed by 5077 | Submission Open

Keywords: synthesis; bonding and structures; reaction mechanism; physical properties; application; germanium; tin

(This special issue belongs to the Section Macromolecules)

Molecular Insight into Oral Diseases

edited by Lorenzo Azzi

submission deadline 20 Aug 2025 | 3 articles | Viewed by 5059 | Submission Open

Keywords: dental caries; periodontal disease; oral cancer; oral potentially malignant disorders; salivary gland disease; oral lichen planus; benign mucous membrane pemphigoid; bullous dermatoses; odontogenic cysts; odontogenic tumors; orofacial pain; human papillomavirus; oral diagnosis; oral pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ocular Ischemic Diseases: From Molecular Mechanisms to Therapeutics

edited by

Deokho Lee

submission deadline 20 Aug 2025 | 2 articles | Viewed by 4899 | Submission Open

Keywords: diabetic retinopathy; retinopathy of prematurity; retinal vein occlusion; retinal artery occlusion; pathologic myopia; age-related macular degeneration; glaucoma; ocular ischemic syndrome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Photosynthesis: Mechanisms of Protein Complex Functioning, Protein Structural Modifications and Protein-Protein Interactions

edited by Ilya B. Kovalenko

submission deadline 20 Aug 2025 | 2 articles | Viewed by 4888 | Submission Open

Keywords: photosynthesis; electron transport; molecular dynamics; proteins; protein-protein interaction; conformational changes; reaction center; mobile electron carrier

(This special issue belongs to the Section Biochemistry)

Mitochondrial Respiration and Energy Metabolism in Cancer Cells

edited by

Rasa Banienė

submission deadline 20 Aug 2025 | 4 articles | Viewed by 4848 | Submission Open

Keywords: mitochondria; respiration; cancer; ATP synthesis; mtDNA; oxidative stress; glycolysis; cell death

(This special issue belongs to the Section Molecular Oncology)

Bone Tissue Engineering: Opportunities and Challenges

edited by

Elisa Mazzoni

and

Maria Rosa Iaquinta

submission deadline 20 Aug 2025 | 4 articles | Viewed by 4806 | Submission Open

Keywords: material; biocompatibility; scaffold; regeneration; bone; osteoinductivity; tissue; stem cells; microenvironment processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Molecular Aspects of Colorectal Cancer

edited by

Christos K. Kontos

submission deadline 20 Aug 2025 | 2 articles | Viewed by 4678 | Submission Open

Keywords: colorectal adenocarcinoma; cancer pathobiology; molecular biomarkers; diagnosis and prognosis; prediction of therapy selection; therapeutic targets; RNA molecules; microRNA; long non-coding RNA; circular RNA

(This special issue belongs to the Section Molecular Oncology)

Advances in Tea Tree Metabolism and Genetics

edited by Xiaoling Sun

submission deadline 20 Aug 2025 | 4 articles | Viewed by 4676 | Submission Open

Keywords: tea tree; secondary metabolite; genetic transformation; genetic breeding; tea germplasm improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Molecular Research on Cancer Treatments: Apoptosis, Autophagy, and Drug Selection

edited by

Md Ataur Rahman

submission deadline 20 Aug 2025 | 2 articles | Viewed by 4663 | Submission Open

Keywords: autophagy; apoptosis; bioactive natural products; nanoparticles and drug delivery; cancer immunotherapy; in silico and network pharmacology; bioinformatics

(This special issue belongs to the Section Molecular Oncology)

Animal Gut Microbial Metagenome

edited by

Shengguo Zhao

submission deadline 20 Aug 2025 | 2 articles | Viewed by 4658 | Submission Open

(This special issue belongs to the Section Molecular Microbiology)

New Trends in Biologically Active Compounds in Age-Related Diseases

edited by Celia Andrés Juan

submission deadline 20 Aug 2025 | 2 articles | Viewed by 4657 | Submission Open

Keywords: age-related diseases; oxidative stress and inflammation; energy failure; mitochondrial dysfunction; deregulated autophagy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research and Therapeutic Targets in Acute Settings: Ischemic and Traumatic Brain Injuries

edited by Hylde Zirpoli

submission deadline 20 Aug 2025 | 2 articles | Viewed by 4604 | Submission Open

Keywords: ischemic brain injury; traumatic brain insult; cell-type specific molecular mechanisms; therapy; target discovery; repurposing; efficacy studies; new drug formulations; high-throughput technologies; proteomics; metabolomics; microarray; next-generation sequencing; BBB disruption; gliosis; neuronal loss; neurobehavior; age-related molecular mechanisms in brain injury

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 751-800 on page 16 of 68.

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