New Molecular Aspects of Colorectal Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 August 2025 | Viewed by 4082
Special Issue Editor
Interests: colorectal cancer; leukemia; tumor biomarkers; anticancer drugs; apoptosis; BCL2 family; alternative splicing; kallikrein-related peptidases (KLKs); nanopore sequencing; next-generation sequencing (NGS)
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Special Issue Information
Dear Colleagues,
Colorectal cancer (CRC) is considered to be one of the most fatal types of cancer worldwide, in both men and women. In recent decades, great progress has been achieved towards the elucidation of the molecular background of CRC and, therefore, a new era in diagnosis, prognosis, and therapeutic approaches has emerged. Moreover, new molecular biomarkers including microRNAs, RNA-derived fragments (e.g., tRNA-derived RNA fragments; tRFs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs) have attracted researchers’ interest. In this perspective, newly characterized biomolecules as well as components of classical signaling pathways, such as the EGFR/KRAS/MAPK and the PI3K/AKT1/mTOR pathways, have been assessed for their potential value as molecular CRC biomarkers and/or therapeutic targets.
This Special Issue focuses on informing the readers regarding novel molecular aspects of CRC and general approaches, which will contribute to further elucidation of the underlying molecular mechanisms. The authors are encouraged to submit their research studies concerning this topic. All studies will be taken into consideration. The Guest Editor is also willing to evaluate manuscripts describing other aspects of CRC pathobiology, as proposed by the authors. I hope that this Special Issue on novel molecular aspects of colorectal cancer will ignite readers’ interest in the this journal.
Dr. Christos K. Kontos
Guest Editor
Manuscript Submission Information
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Keywords
- colorectal adenocarcinoma
- cancer pathobiology
- molecular biomarkers
- diagnosis and prognosis
- prediction of therapy selection
- therapeutic targets
- RNA molecules
- microRNA
- long non-coding RNA
- circular RNA
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