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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Understanding and Combating Antimicrobial Resistance: Molecular Insights and Innovative Approaches

edited by

Giovanni Di Bonaventura

submission deadline 30 Nov 2026 | Viewed by 444 | Submission Open

Keywords: genetic mutations; horizontal gene transfer; efflux pump mechanisms; biofilm formation; novel antibiotic development; antimicrobial peptides; phage therapy; CRISPR-based tools; antimicrobial stewardship programs

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Periodontitis

edited by Maja Miletić and

Natasa Nikolic-Jakoba

submission deadline 30 Nov 2026 | 1 articles | Viewed by 440 | Submission Open

Keywords: periodontitis; molecular mechanisms; inflammation; oral microbiome; multi-omics; biomarkers; cytokines; oxidative stress; immune regulation; tissue regeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances of Layered Double Hydroxides (LDH) for Corrosion Protection

edited by

Henryk Kania

submission deadline 30 Nov 2026 | Viewed by 435 | Submission Open

Keywords: layered double hydroxide (LDHs); corrosion resistance; coatings; corrosion products

(This special issue belongs to the Section Materials Science)

Molecular Progress in Male Reproduction

edited by

Ahmet Ayaz

submission deadline 30 Nov 2026 | Viewed by 435 | Submission Open

Keywords: male infertility; spermatogenesis; epigenetics; sperm function; testicular molecular biology; bioinformatics; reproductive genomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Research in Leukemia

edited by

Juan Manuel Mejia-Arangure

submission deadline 30 Nov 2026 | Viewed by 427 | Submission Open

Keywords: leukemia; molecular biology; genetic testing; epigenomics; targeted therapy; precision medicine; diagnostic techniques; molecular pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Stress Signaling in Embryonic Development

edited by

Poongodi Geetha-Loganathan

and Norihisa Higashihori

submission deadline 30 Nov 2026 | Viewed by 426 | Submission Open

Keywords: stress signaling; embryonic development; morphogenesis; signal transduction; teratogenesis

(This special issue belongs to the Section Molecular Biology)

The Role of Transcription Factors in Cancer

edited by

Tomasz Wilanowski

submission deadline 30 Nov 2026 | Viewed by 425 | Submission Open

Keywords: transcription factor; oncogene; tumor suppressor; nuclear receptor; genetic regulation; post-translational regulation; biomarker; drug target

(This special issue belongs to the Section Molecular Oncology)

Research of Aldo-Keto Reductases in Human Disease

edited by

Ping Zhu

and

Hao Luo

submission deadline 30 Nov 2026 | 1 articles | Viewed by 423 | Submission Open

Keywords: aldo-keto reductase (AKR); protein engineering; AKR1B10; cancer biomarker; chemoresistance

(This special issue belongs to the Section Biochemistry)

Antimicrobial Agents and the Quest for Resistance Breakthroughs

edited by

Inês Bártolo

submission deadline 30 Nov 2026 | Viewed by 419 | Submission Open

Keywords: drug resistance; antimicrobial resistance (AMR); drug-resistant bacteria; drug-resistant viruses; drug-resistant fungi; drug-resistant parasite; drug resistance biomolecular studies; mechanism of resistance; novel antimicrobial agents; treatment of infectious diseases

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Application of Biomaterial in Skin Diseases

edited by

Danuta Nowicka

submission deadline 30 Nov 2026 | Viewed by 416 | Submission Open

Keywords: chronic dermatoses; autologus material; PRP; stem cells; growth factors

(This special issue belongs to the Section Materials Science)

Plant–Microbe Interactions Driving Abiotic Stress Adaptation

edited by Saeed Ur Rahman and Nan Hui

submission deadline 30 Nov 2026 | Viewed by 414 | Submission Open

Keywords: plant–microbe interactions; abiotic stress; rhizosphere microbiome; stress tolerance; horticultural crops; molecular mechanisms; plant growth-promoting microbes; omics approaches; sustainable agriculture; signaling pathways

(This special issue belongs to the Section Molecular Plant Sciences)

Vascular Calcification: Molecular Regulation, Inflammation and Translational Perspectives

edited by

Laia Cañes

submission deadline 30 Nov 2026 | Viewed by 413 | Submission Open

Keywords: vascular calcification; inflammation; calcium-phosphate alterations; osteogenic differentiation; vascular smooth muscle cells; cardiovascular disease

(This special issue belongs to the Section Molecular Biology)

Recent Genetic Insights into Neurodevelopmental Disorders

edited by Maria Cristina Aspromonte and Emanuela Dazzo

submission deadline 30 Nov 2026 | Viewed by 407 | Submission Open

Keywords: neurodevelopmental disorders; autism spectrum disorder; intellectual disability; attention deficit hyperactivity disorder; epilepsy; motor disorders; chromosomal rearrangements; genetic variant; integrative omics approaches

(This special issue belongs to the Section Molecular Neurobiology)

The Role of Dopamine Neurotransmission in Schizophrenia

edited by

Mirian Akemi Furuie Hayashi

submission deadline 30 Nov 2026 | Viewed by 407 | Submission Open

Keywords: schizophrenia; dopamine; dopaminergic system; neurotransmission; psychosis; pathophysiology; molecular psychiatry

(This special issue belongs to the Section Molecular Neurobiology)

Advances in the Molecular Biology of Lipids and Mitochondria

edited by

Alejandra Espinosa

submission deadline 30 Nov 2026 | Viewed by 403 | Submission Open

Keywords: lipids; lipid transport mechanisms; lipid peroxidation; mitochondrial integrity; bioenergetics; mitochondrial phospholipid

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Mechanisms in Mucosal Immunity

edited by

Mónica Vermeulen

submission deadline 30 Nov 2026 | Viewed by 398 | Submission Open

Keywords: mucosal immunity; metabolism; innate memory; trainers and inflammatory stimuli

(This special issue belongs to the Section Molecular Immunology)

Integrative Regenerative Medicine: Bridging Molecular Mechanisms and Therapeutic Applications

edited by

Jerran Santos

submission deadline 30 Nov 2026 | Viewed by 396 | Submission Open

Keywords: regenerative medicine; stem cells; molecular mechanisms; tissue engineering; organoids; biomaterials; biofabrication; clinical translation; cell therapy; integrative biology

(This special issue belongs to the Section Molecular Biology)

Advances in Research on Neurotransmitters (Second Edition)

edited by

Mario Manto

Hiroshi Mitoma

and Jing-Ning Zhu

submission deadline 30 Nov 2026 | 1 articles | Viewed by 394 | Submission Open

Keywords: neurotransmitters; GABA; glutamate; monoamines; dopamine; serotonin; norepinephrine; neuropeptides; nitric oxide; neurosteroids; stress; neurotrophins; epigenetics; gut–brain axis

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Osteogenesis: 2nd Edition

edited by

Andrea Del Fattore

submission deadline 30 Nov 2026 | Viewed by 392 | Submission Open

Keywords: osteogenesis; osteoblast; bone formation; disease; bone

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Magnetic Nanoparticles: From Synthesis and Modification to Biomedical Applications

edited by

Ahmet Kertmen

submission deadline 30 Nov 2026 | Viewed by 386 | Submission Open

Keywords: magnetite nanoparticles; colloidal interactions; X-ray characterizations; biomedical applications; method development; imaging

(This special issue belongs to the Section Molecular Nanoscience)

Apoptosis in Health and Disease: Recent Advances and Future Directions

edited by Shabnam Malik

submission deadline 30 Nov 2026 | Viewed by 382 | Submission Open

Keywords: apoptosis; programmed cell death; health and disease; cellular homeostasis; cancer; neurodegenerative disorders

(This special issue belongs to the Section Molecular Biology)

Oxidative Stress, Biomarkers and Dysregulated Lipid Metabolism in Cardiovascular Diseases

edited by

Amilia Aminuddin

and Adila Abdul A. Hamid

submission deadline 30 Nov 2026 | 1 articles | Viewed by 377 | Submission Open

Keywords: cardiovascular diseases; oxidative stress; lipid metabolism; atherosclerosis; endothelial dysfunction; inflammation; biomarkers; reactive oxygen species (ROS); dyslipidemia; vascular function

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Therapeutic Strategies for Surgical Tissue Damage, Repair and Regeneration

edited by

Alex K. Wong

submission deadline 30 Nov 2026 | Viewed by 377 | Submission Open

Keywords: surgical injury; tissue regeneration; vasculogenesis; wound healing in compromised settings; molecular therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant–Microbe Interactions in Alleviation of Abiotic Stress in Plants

edited by

Marzena Sujkowska-Rybkowska

submission deadline 30 Nov 2026 | Viewed by 376 | Submission Open

Keywords: abiotic stresses; plant–microbe interactions; symbiotic microbes; stress adaptation; stress-responsive genes; physio-logical responses

(This special issue belongs to the Section Molecular Plant Sciences)

Antiviral Drug Target Discovery and Design

edited by

Dongwei Kang

and Huajun Zhao

submission deadline 30 Nov 2026 | Viewed by 373 | Submission Open

Keywords: antiviral; drug discovery; drug resistance; immune and pharmacological mechanisms; immunotherapy; immunopathology; vaccines and adjuvants

(This special issue belongs to the Section Molecular Pharmacology)

Roles and Mechanisms of Non-Coding RNAs in Human Health and Disease: 2nd Edition

edited by

Marco Ragusa

and

Cristina Barbagallo

submission deadline 30 Nov 2026 | Viewed by 368 | Submission Open

Keywords: non-coding RNAs; microRNAs; long non-coding RNAs; circular RNAs; biomarkers; polymorphisms; cancer; degenerative diseases; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Insight into Pathogen Stress Effects on Plant Structure and Metabolism

edited by

Edmund Kozieł

and

Katarzyna Otulak-Kozieł

submission deadline 30 Nov 2026 | Viewed by 368 | Submission Open

Keywords: plant–pathogen interaction; innate immunity; ultrastructure; plant defense systems; plant physiology; signal transduction; resistance genes

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insight into Polymer Dynamics

edited by

Sirui Ge

submission deadline 30 Nov 2026 | Viewed by 367 | Submission Open

Keywords: polymer dynamics; glass transition; segmental relaxation; bulk relaxation; structure–property relationship; functional polymers; spectroscopy; instrumental characterization; simulations and modeling; polymer diffusion

(This special issue belongs to the Section Materials Science)

RNA Structure, Folding and Cellular Function: Mechanisms and Biological Significance

edited by

Ilias Skeparnias

submission deadline 30 Nov 2026 | Viewed by 350 | Submission Open

Keywords: RNA structure; RNA folding; RNA–protein interactions; R-loops; RNA:DNA hybrids; non-coding RNA; RNA biogenesis; gene regulation; ribozymes; RNA therapeutics

(This special issue belongs to the Section Molecular Biology)

Advances in the Reprogramming of Mitochondrial Signalling and Metabolism in Cancers

edited by

Maria Rosa Ciriolo

and

Fabio Ciccarone

submission deadline 30 Nov 2026 | Viewed by 348 | Submission Open

Keywords: mitochondrial dynamic; mitochondrial biogenesis; mitochondrial transfer; mitochondrial targeting; mitophagy; oxidative metabolism; mtDNA; ROS; oncometabolism

(This special issue belongs to the Section Molecular Oncology)

Natural Product Research: From Isolation to Functional Validation

edited by

Radosław Kowalski

submission deadline 30 Nov 2026 | Viewed by 347 | Submission Open

Keywords: natural products; secondary metabolites; bioactive compounds; extraction and isolation; green extraction; structural elucidation; metabolomics profiling (LC–HRMS/MS); dereplication; functional validation; molecular mechanisms; molecular docking; molecular modeling; ligand–protein interactions; structure–activity relationship (SAR); in vitro and in vivo studies; bioavailability and safety; antimicrobial activity; antioxidant activity; anticancer activity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Advances in Brucella Research

edited by

Angel Oñate

submission deadline 30 Nov 2026 | Viewed by 344 | Submission Open

Keywords: Brucella abortus; molecular pathogenesis; host–pathogen interaction; virulence factors; oxidative stress response; intracellular survival; immune evasion; exosomes; vaccine development

(This special issue belongs to the Section Molecular Microbiology)

Stem Cell Research in Urological, Hepatological, and Ophthalmological Disorders

edited by Yuanyuan Zhang

submission deadline 30 Nov 2026 | Viewed by 343 | Submission Open

Keywords: stem cells; induced pluripotent stem cells (iPSCs); exosomes; tissue regeneration; urinary incontinence; kidney dysfunction; ocular disorders; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

The Role of Ferroptosis in Cancer Biology and Therapy

edited by Alessandra Di Paola and Elvira Pota

submission deadline 30 Nov 2026 | Viewed by 332 | Submission Open

Keywords: ferroptosis; cancer biology; tumor microenvironment; therapeutic targeting; anticancer immunity; targeted therapy

(This special issue belongs to the Section Molecular Oncology)

Hydrogels and Nanogels: Revolutionizing Drug Delivery and Disease Detection

edited by Enrico Gallo

submission deadline 30 Nov 2026 | Viewed by 325 | Submission Open

Keywords: hydrogel and nanogel networks; supramolecular systems; hydrogel synthesis and analysis; nanogel preparation and characterization; nanostructured fibers; multiphase gels; biomedicine applications; supramolecular probes for imaging; hydrogels and nanogels as drug release systems; coatings and surface treatments; polymeric systems; peptide-based supramolecular systems

(This special issue belongs to the Section Materials Science)

Innovative Nano- and Microcarrier Systems for Targeted Delivery

edited by

Matteo Perra

submission deadline 30 Nov 2026 | Viewed by 323 | Submission Open

Keywords: drug delivery systems; nanocarriers; microcarriers; targeted delivery; controlled release; bioactive compounds; nanomedicine

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Interactions Between Bacteria and Viruses: Mechanisms and Pathogenic Insights

edited by Vasilis Petrakis

submission deadline 30 Nov 2026 | Viewed by 323 | Submission Open

Keywords: viral infections; HIV/AIDS; SARS-CoV-2; antibiotics; antimicrobial resistance; antiviral agents

(This special issue belongs to the Section Molecular Microbiology)

Gene Therapy for Ocular Diseases: Mechanisms, Advances and Therapeutic Applications

edited by Jiang-Hui Wang

submission deadline 30 Nov 2026 | Viewed by 323 | Submission Open

Keywords: AAV; capsid engineering; gene therapy; retinal diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in the Diagnosis and Treatment of Cardiovascular Disease and Diabetes Mellitus

edited by Ovidiu Nicolae Pop and

Cosmin Mihai Vesa

submission deadline 30 Nov 2026 | Viewed by 321 | Submission Open

Keywords: cardiovascular disease; diabetes mellitus; molecular medicine; precision medicine; cardiometabolic disease; biomarkers; inflammation; oxidative stress; epigenetics; non-coding rna; sglt2 inhibitors; glp-1 receptor agonists; gene therapy; regenerative medicine; translational therapeutics; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pharmacognosy and Phytochemical Profiling in Natural Product Research

edited by Kamran Ashraf

submission deadline 30 Nov 2026 | Viewed by 321 | Submission Open

Keywords: molecular pharmacognosy; phytochemical profiling; natural products; bioactive compounds; metabolomics; chemometrics; LC–MS/MS; GC–MS; molecular mechanisms; drug discovery

(This special issue belongs to the Section Molecular Plant Sciences)

Endometrial Cancer: From Molecular Mechanisms to Treatment

edited by Ursula Catena

submission deadline 30 Nov 2026 | Viewed by 316 | Submission Open

Keywords: endometrial cancer; molecular mechanisms; biomarkers; targeted therapy; immunotherapy; genomics; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms, Epigenetics and Therapeutics in Liver Cirrhosis

edited by Ana Soledad Sandoval-Rodríguez

submission deadline 30 Nov 2026 | Viewed by 316 | Submission Open

Keywords: liver cirrhosis; molecular pathogenesis; fibrosis and inflammation; epigenetics; hepatocellular carcinoma (HCC); viral hepatitis; molecular mechanism; hepatic nutrition; therapeutic targets; translational hepatology; MASLD; ALD

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research in DNA Methylation

edited by Mikhail M. Baryshev

submission deadline 30 Nov 2026 | Viewed by 312 | Submission Open

Keywords: DNA methylation; cancer-specific DNA methylation; epigenetics; lncRNA; CpG, CHG, CHH, CCWGG methylation types; chromatin remodeling

(This special issue belongs to the Section Biochemistry)

Molecular Research on Foodborne Pathogens and Biofilms

edited by

Arturo Ramirez-Peralta

submission deadline 30 Nov 2026 | Viewed by 309 | Submission Open

Keywords: foodborne pathogens; biofilms; food

(This special issue belongs to the Section Molecular Microbiology)

Deep Learning Biomarkers for Cancer Therapy

edited by

Hüseyin Fırat

submission deadline 30 Nov 2026 | Viewed by 308 | Submission Open

Keywords: deep learning; cancer biomarkers; precision oncology; histopathology; medical imaging; explainable AI; cancer detection; cancer segmentation; digital pathology; clinical decision support

(This special issue belongs to the Section Molecular Oncology)

Advances in Pharmacogenomics and Drug Repositioning

edited by

Vasudevan Ramachandran

and

Suresh Kumar

submission deadline 30 Nov 2026 | Viewed by 308 | Submission Open

Keywords: risk prediction; gene–drug interactions; genetic polymorphisms; repurposed drugs; integrative analytics; variant mapping; predictive modeling; molecular docking; cheminformatics; genotype-guided therapy; real-world evidence

(This special issue belongs to the Section Molecular Pharmacology)

Bioactive Phenolic Compounds in Human Health and Disease: Second Edition

edited by

Andrei Lobiuc

submission deadline 30 Nov 2026 | Viewed by 306 | Submission Open

Keywords: novel sources; synthesis; biological activity; molecular interactions; pharmacodynamics; pharmacokinetics; assay development; microbiota; sources and intake

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Design, Synthesis, and Application of Functional Porous Materials

edited by Qinhe Pan,

Shenzhen Chang

and

Shi-Cheng Wang

submission deadline 30 Nov 2026 | Viewed by 301 | Submission Open

Keywords: porous materials; functional guest species; functionalization; luminescence; electrochemistry; stimulus response; adsorption; sensing; photoelectric; catalysis

(This special issue belongs to the Section Materials Science)

Research on Molecular Mechanisms of Food Quality Regulation

edited by Jun Yan

submission deadline 30 Nov 2026 | Viewed by 288 | Submission Open

Keywords: food quality regulation; molecular mechanism; omics technology; food macromolecules; postharvest preservation; gene transcription regulation

(This special issue belongs to the Section Molecular Biology)

Molecular Biomarkers and Precision Medicine in Cancer

edited by Ana Ĺivia Silva Galbiatti-Dias

submission deadline 30 Nov 2026 | Viewed by 287 | Submission Open

Keywords: biomarkers; RNA; cancer; exosomes

(This special issue belongs to the Section Molecular Oncology)

Displaying special issue 1451-1500 on page 30 of 61.

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