Understanding and Combating Antimicrobial Resistance: Molecular Insights and Innovative Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 17
Special Issue Editor
Interests: biofilm formation mechanisms; role of biofilm formation in the pathogenesis of cystic fibrosis lung infections; drug repurposing to identify new molecules with antibacterial activity; antibiofilm strategies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antimicrobial resistance (AMR) poses a critical threat to global public health, compromising the effectiveness of life-saving drugs and complicating the treatment of infectious diseases. This special issue brings together cutting-edge research and comprehensive reviews that delve into the molecular underpinnings of AMR, including genetic mutations, horizontal gene transfer, efflux pump mechanisms, and biofilm formation. In parallel, it highlights innovative strategies to counteract resistance, such as novel antibiotic development, antimicrobial peptides, bacteriophage therapy, CRISPR-based tools, and antimicrobial stewardship programs. By bridging fundamental molecular science with applied solutions, this issue aims to foster a deeper understanding of resistance mechanisms and inspire transformative approaches to restore the efficacy of antimicrobial therapies.
Scope and Topics of Interest Include (but are not limited to):
- Molecular and genetic mechanisms underlying AMR
- Evolution and spread of resistance genes and mobile genetic elements
- Cutting-edge diagnostics and resistance detection tools
- Development of novel antimicrobials and drug repurposing
- Phage therapy, antimicrobial peptides, and CRISPR-based strategies
- Biofilms and host–pathogen interactions
- Global surveillance, One Health initiatives, and resistance mitigation policies
Dr. Giovanni Di Bonaventura
Guest Editor
Manuscript Submission Information
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Keywords
- genetic mutations
- horizontal gene transfer
- efflux pump mechanisms
- biofilm formation
- novel antibiotic development
- antimicrobial peptides
- phage therapy
- CRISPR-based tools
- antimicrobial stewardship programs
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