Special Issue "Functions of Transfer RNAs 2.0"
Deadline for manuscript submissions: closed (31 March 2018).
Prof. Dr. Lluís Ribas de Pouplana
Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Parc Científic de Barcelona, C/Baldiri Reixac 10, 08028 Barcelona, Catalonia, Spain
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Interests: genetic code; genetic translation; codon usage; proteome control; tRNAs; ribosomes; proteome quality control in cell biology and disease; structure-function studies of protein-RNA interactions; biomedicine and biotechnology
Transfer RNA (tRNA) has been in the focus of molecular biology since its central role in translating the genetic code was first predicted by Crick, over 60 years ago. Despite this long history, exciting new revelations continue to be discovered around tRNA, a consequence of its intricate integration with all aspects of cell biology.
Current interest in tRNA is far from limited to its canonical role in translation, and extends now to metabolism, cell signaling, stress responses, and a range of medical conditions from infectious diseases to cancer. Continuing from an issue of IJMS that was published to celebrate the 50th anniversary of the international tRNA meeting, we will assemble a second collection of articles to summarize the state-of-the-art regarding the many angles that tRNA research takes today. Once again, this issue will cover the evolution of the molecule and the genetic code, tRNA synthesis and cellular distribution, roles in translation, signaling connections between tRNAs and regulatory pathways, roles in disease, and biotechnological advances. We hope to provide, once again, a useful compilation of the latest developments in tRNA biology.Prof. Dr. Lluís Ribas de Pouplana
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- transfer RNA
- genetic code
- codon recognition
- aminoacyl-tRNA synthesis
- protein synthesis
- synthetic biology
- tRNA-dependent regulation
- posttranscriptional modifications