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Translational Molecular Medicine & Molecular Drug Discovery

This special issue belongs to the section “Biochemistry“.

Special Issue Information

Dear Colleagues,

There is a growing consensus that the transfer of knowledge from biomedical science into clinical application should be accelerated. Translational molecular medicine offers an opportunity for applying the research discoveries obtained from basic research to every-day clinical applications for the prevention, diagnosis, and treatment of human diseases. Translational molecular medicine is the integrated application of innovative pharmacology tools, biomedical engineering technology, omics technologies, biomarkers discovery, and clinical technologies to improve the disease understanding of the molecular mechanisms. Molecular drug discovery is a long and complex process that utilizes multidisciplinary project teams and attempts to simultaneously move forward with as many aspects of the overall drug discovery and development process as possible. Modern methodologies of molecular drug discovery include high throughput screening, natural product separation, chemical synthesis and modification, omics technologies, data mining, structure-based drug design, ADME/T (absorption, distribution, metabolism, excretion/toxicity) evaluation, target and lead identification and validation, systems biology and systems pharmacology based drug discovery, structural biology, knowledge-based design of drug combinations and multi-target drugs, phenotypic screening, etc. As the interdisciplinary branch and hot topic of precision medicine, translational molecular medicine and molecular drug discovery have gained more and more attention in recent years.

This Special Issue, “Translational Molecular Medicine and Molecular Drug Discovery”, will cover a selection of recent research topics and current review articles in the field. Experimental papers, up-to-date review, and commentaries are all welcome.

Assoc. Prof. Dr. Ge Zhang
Prof. Dr. Aiping Lu
Assist. Prof. Dr. Hailong Zhu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • translational medicine
  • molecular mechanism
  • biomarkers
  • drug discovery
  • omics technologies
  • chemical synthesis
  • data mining
  • systems biology
  • systems pharmacology
  • drug design
  • transcriptional regulation network
  • next generation sequencing
  • modeling

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Int. J. Mol. Sci. - ISSN 1422-0067