Protein Engineering

Dear Colleagues,

The world demand for protein-based reagents has increased tremendously. Recent progress in protein engineering through rational design and directed evolution in animal, plant, and microorganisms has created novel protein molecules with greatly enhanced functionality and utility. Advancements in high throughput technology also facilitate that pace of these proteins’ identification. These engineered proteins include biologics (such as human and animal vaccines and different monoclonal antibody variants, which act as therapeutics with enhanced efficacy and safety in preventing and treating diseases) and industry enzymes with increased catalytic efficiency and stability (or with novel substrate or cofactor specificity for biofuel production and manufacturing or for new low-cost materials).

This Special Issue invites original research and review manuscripts that report the recent developments and applications of protein engineering with respect to topics that include, but are not limited to:

• Novel strategy, methodology, and platform development
• Rational protein design, directed evolution, and high-throughput screening
• Protein folding and unnatural amino acids
• Novel engineered protein products
• Vaccines, immunotherapeutics, monoclonal antibodies
• Enzymes for biofuel and new material production
• Glycoengineering and posttranslational modification
• Novel protein engineering organism hosts
• Extraction, recovery, and purification of engineered proteins
• Economic impact and evaluation

Dr. Qiang "Shawn" Chen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.