Prostate Cancer: Pathology, Pathobiology and Therapy

Dear Colleagues,

Prostate cancer is the most common malignancy (after skin cancer) and the second leading cause of cancer-related death among US men. The incidence of prostate cancer has also been increasing steadily worldwide. Due to disease heterogeneity, patients with prostate cancer show a range of prognoses and different treatment outcomes. Disparate incidence and clinical outcomes in different racial and ethnic groups are also common even when accounted for socioeconomic variables further adding to the complexity of the disease biology. Moreover, there is a lack of specific biomarkers leading to overdiagnosis of prostate cancer, which in turn results in unnecessary treatment, economic burden and psychological stress to the patients and their families. Clearly, an improved understanding of the prostate cancer pathology and pathobiology is critical to develop novel approaches for prostate cancer diagnosis, prognosis and therapy.

This Special Issue seeks research and review manuscripts focusing on the molecular and cellular basis of prostate cancer, biomarkers and emerging advances in disease stratification, mechanisms underlying therapeutic failure, aggressive behavior, and evaluation of novel therapeutic interventions.

Prof. Dr. Ajay Pratap Singh
Dr. Debanjan Chakroborty
Guest Editors

Manuscript Submission Information

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