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Multi-Drug Resistant Bacteria—A Global Problem

This special issue belongs to the section “Molecular Microbiology“.

Special Issue Information

Dear Colleagues,

The growing number of isolated multi-drug resistant clinical and environmental bacterial strains and the ability to produce and transmit resistance mechanisms to antibiotics and antibacterial chemotherapeutics have become an increasing problem in combating worldwide infections in recent years. As the WHO points out, one of the main elements in fighting the problem of microbial resistance is an in-depth understanding of the underlying resistance mechanisms. In this Special Issue, we plan to collect original research articles and review articles concerning the molecular basis of resistance mechanisms against antimicrobial agents (e.g., antibiotics, new antibacterial substances and disinfectants) in Gram-positive and Gram-negative bacteria. These strains may be present in the natural environment (water, soil and air) and healthcare environment and, mostly, can be isolated from clinical and veterinary materials. The multi-drug resistance observed in bacterial strains is due to the acquisition and interaction of several various resistance mechanisms. Today, the most dangerous are resistance genes localized in mobile genetic elements.

Prof. Dr. Agnieszka Laudy
Guest Editor

Prof. Dr. Stefan Tyski
co-Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • MDR bacterial strains
  • Drug-resistance mechanisms
  • Antibiotic-resistance genes
  • Acquired resistance
  • Mobile genetic elements
  • Transmission of resistance genes
  • Regulation of resistance-gene expression
  • Enzymatic mechanisms of drug resistance
  • Beta-lactamases
  • Efflux pumps
  • Drug influx
  • Cell wall and outer membrane porins
  • Cell membrane permeability
  • Modification of enzymatic pathways
  • Antibacterial-agent targets
  • New antibacterial agents
  • Resistance to antibiotics
  • Resistance to antimicrobial agents
  • Resistance to antiseptics and disinfectants
  • Bacterial pathogenic strains
  • Resistant environmental strains
  • Resistant clinical strains

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Int. J. Mol. Sci. - ISSN 1422-0067