Special Issue "Novel Insights on the Molecular Bases of Hormone-Responsive Breast Cancer Biology"
Deadline for manuscript submissions: 31 October 2020.
Interests: cancer biology; functional genomics; epigenomics; chromatin remodelling; endocrine-resistance; interaction proteomics
Breast cancer (BC) is one of the most frequent neoplasia in women and presents multiple patterns of disease progression and response to therapies, mainly relying on the expression of hormone receptors.
Approximately 70% of breast tumors express estrogen receptor α (ERα), most showing hormone dependence and responding to adjuvant endocrine therapies. Although ER blockade is effective in the majority of cases, intrinsic or de novo resistance to endocrine therapy of receptor-positive tumors is a key problem in clinical management of BC patients.
This Special Issue “Novel Insights on the Molecular Bases of Hormone-Responsive Breast Cancer Biology” of the International Journal of Molecular Sciences aims to provide an updated overview of basic and translational research focusing on hormone-responsive and/or endocrine-therapy resistant breast cancer at the molecular level. In vitro, in vivo, and ex vivo experimental models, multi-omics, and genome-wide approaches are welcome.
The formats for submissions include original research articles, brief communications, and reviews.
Prof. Dr. Roberta Tarallo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- breast cancer
- estrogen signaling
- endocrine resistance
- molecular mechanisms
- epigenetic modifications
- chromatin remodeling
- omics approaches
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: An unexpected impact of an HCV inhibitor on estradiol signaling in breast cancer
Authors: Filippo Acconcia, etc.
Title: MiRNA signatures in ER positive breast cancer - implications in biology, prognosis, preventive and personalised medicine
Authors: Erik Kudela, etc.
Title: Adipose tissue and breast cancer: a bibliometric analysis of expression and variation of some important adipose biomarkers
Authors: Dinh-Toi Chu, Thuy Nguyen Thi Phuong, Thien Chu Dinh, etc.
Title: The importance of breast adipose tissue in breast cancer
Authors: Charu Kothari, Caroline Diorio and Francine Durocher