Special Issue "A Commemorative Issue in Honor of Professor Nick Hadjiliadis: Metal Complex Interactions with Nucleic Acids and/or DNA"
Deadline for manuscript submissions: closed (31 May 2018)
A printed edition of this Special Issue is available here.
Prof. Dr. Sotiris K Hadjikakou
Biological Inorganic Chemistry Lab, Department of Chemistry, University of Ioannina, Ioannina, Greece
Website | E-Mail
Phone: +30-26510-08374 (office); +30-26510-08362 (lab)
Interests: Inorganic Biochemistry; design and development of new metallotherapeutic compounds; new metal drugs against tumor cells or microbes; antibiotics and NSAID’s modifications; alternative disinfectants
Dr. Christina N. Banti
Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece
Interests: bioinorganic chemistry; evaluation of the anticancer properties of metal complexes by studying their interaction with intracellular molecules
This special issue entitled "Metal complexes interactions with Nucleic acids and/or DNA" was inspired by Prof. Sotiris Hadjikakou, due to the contribution of Prof. Nick Hadjiliadis in the field of palladium or/and platinum/nucleic acids interactions. It will cover a selection of recent research and review articles in the field of Metal complexes interactions with Nucleic acids and/or DNA.
Metal complexes have long been recognized as critically important components of nucleic acid chemistry, both in regulation of gene expression and as promising therapeutic agents. The ability to recognize, to understand at the molecular level of how metal complexes interact with DNA has become an active research area at the interface between biological inorganic chemistry, molecular biology and medicine.
Arguably, the most prominent drug which contains a metal is cisplatin, the most widely used anti-cancer drug. The success of cisplatin in chemotherapy and the clarification of its mechanism of action through interaction with DNA has motivated a large number of studies on metal complexes interaction with nucleic acids or/and DNA. From the foregoing that the reader of this special issue will gain an appreciation of the real role of the interactions of metal complexes with nucleic acids or/and DNA in modern medicine.
This special issue on the "Metal complexes interactions with Nucleic acids and/or DNA" aims to provide an overview of this increasingly diverse field, presenting recent developments and the latest research with particular emphasis on metal-based drugs and metal ion toxicity.
Prof. Dr. Sotiris Hadjikakou
Dr. Christina N. Banti
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Biological inorganic chemistry
- Metal complexes interactions with nucleic acids
- Metal complexes interactions with DNA
- Metal-based drugs
- Platinum complexes anticancer agents
- Non-platinum metal complexes anticancer agents