New Insights into the Molecular Mechanisms of Kidney Injury and Repair

Dear Colleagues,

The kidneys are important organs responsible for clearing waste products, salts, and water from the human body. The main physiological functions of kidneys include excretion of wastes, reabsorption of vital nutrients, acid-base homeostasis, maintenance of electrolyte–water balance, and hormone secretion. When kidney function is reduced to less than 15% by acute or chronic insults, a variety of health problems can be caused, such as coagulation abnormalities, cardiovascular dysfunction, vascular calcification, cancer, and cognitive disorders. Repeated unresolved damage after acute or chronic kidney injury leads to maladaptive repair and accelerated renal fibrosis by inducing deregulation of redox homeostasis and inflammatory response, as well as the senescence and death of renal tubular cells. However, the cellular and molecular mechanisms underlying the pathology of kidney diseases are not fully understood. Currently, the treatment of kidney diseases is not optimal; unraveling the mechanisms underlying the pathogenesis of kidney diseases will help develop the new therapeutic strategy for the treatment of kidney diseases. To this end, we sincerely invite researchers to contribute their research works to the Special Issue, entitled "Molecular Mechanisms of Kidney Injury and Repair", which aims to provide a research platform for the collection of original research articles and the latest reviews which cover all aspects of kidney diseases.

Prof. Dr. Tzong-Shyuan Lee
Guest Editor

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