Cytogenomics

Dear Colleagues,

Chromosome biology and medical (cyto)genetics have benefited a lot from the introduction of high-resolution analysis of the human genome. As a result, cytogenomics emerged about a dozen years ago. Currently, cytogenomic research is an important part of genomics and human genetics and is required for the accumulation of knowledge about evolution, structure and behavior of metaphase and interphase chromosomes. Moreover, cytogenomics provides key insights into the mechanisms and spectrum of chromosomal variations in health and disease. In practical medicine, cytogenomic analysis has become a wide area of diagnostic research targeting microscopic and submicroscopic genome variations (chromosome abnormalities), which are the most frequent inherited and acquired genetic causes of human morbidity and mortality. It is thus hard to overestimate the relevance of cytogenomics to biomedicine.

This special issue is a venue for a broad spectrum of articles dedicated to the field of cytogenomics, as a whole. Briefly, structural, behavioral, evolutionary and functional aspects of chromosomes are to be covered. We believe that a collection of papers encompassing different cytogenomic dimensions represents a valuable contribution to bimolecular science.

Prof. Dr. Ivan Y. Iourov
Guest Editor

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