Autophagy in Health, Ageing and Disease 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 82258
Special Issue Editors
2. Center for Research on Aging and Translational Medicine (CeSI-MeT), “G. d’Annunzio” University of Chieti, 66100 Chieti, Italy
Interests: oxidative/nitrosative stress; neurodegenerative diseases
Special Issues, Collections and Topics in MDPI journals
Interests: oxidative/nitrosative stress; cell signalling; tissue repair; neurodegenerative diseases
Special Issues, Collections and Topics in MDPI journals
Interests: autophagy; apoptosis; myokines; oxidative stress; inflammation; aging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autophagy is an evolutionarily conserved intracellular catabolic process. It has an essential role in cellular homeostasis, facilitating lysosomal degradation and the recycling of harmful and damaged cytoplasmic components. Autophagy was first discovered as a survival mechanism in yeasts subjected to nutrient deprivation, and since then, studies in several different organisms have established its critical roles in a variety of biological processes ranging from development to aging. Interestingly, autophagy is often found perturbed in age-related disorders such as cancer, diabetes, neurodegenerative diseases, and sarcopenia. Accordingly, autophagy is important for the maintenance of organismal health, which prominently declines with aging.
This Special Issue of the International Journal of Molecular Sciences, “Autophagy in Health, Ageing, and Disease”, will include a selection of original articles and reviews aimed at expanding our understanding of this multifaceted process and providing support for further investigations on the role of autophagy in cellular homeostasis, aging, and disease. In particular, it will contribute to better explaining the complex machinery of autophagy and lead to further investigations on physiological and pathological fields in which the study of this process is still in its infancy. Moreover, studies on the role of autophagy in age-related processes to open new avenues for the development of novel potential anti-aging therapeutic approaches are also welcome.
Prof. Patrizia Ballerini
Prof. Dr. Antonia Patruno
Dr. Mirko Pesce
Guest Editors
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Keywords
- Autophagy
- Aging
- Aging diseases
- Cell survival
- Inflammation
- Oxidative stress
- Signaling pathway
- Target identification
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