Arginine Metabolism

Dear Colleagues,

This Special Issue, “Arginine Metabolism”, will cover a selection of recent research topics and current review articles related to the role of arginine in health and disease. Up-to-date review articles, commentaries, and experimental papers are all welcome.

Arginine plays a central role as amino acid in various conditions, especially as substrate for different enzymes involved in cellular processes. This is especially true for the generation of nitric oxide (NO) in vascular health and disease. In addition, arginine serves as substrate of arginase, which is also important in regulating vascular function. It has been shown to be of relevance in endothelial cells and also in other cell types such as red blood cells. Over the past decades, numerous articles have shown that this is of interest in cardiovascular disease, diabetes mellitus and its complications, cancer, and inflammatory diseases. In addition, arginine is central in cell development and cell hemostasis. Translational aspects are also welcome, for example, studies dealing with vascular function in the context of arterial hypertension, microvascular dysfunction, or modern, innovative possible treatment strategies.

Prof. Dr. Christian Jung
Prof. Dr. John Pernow
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.