Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
8.1
4.9
Journals
IJMS
Special Issues
Magnetic Nanoparticles for Biomedical and Imaging Applications 2.0
ijms-logo
Submit to IJMS Review for IJMS Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Magnetic Nanoparticles for Biomedical and Imaging Applications 2.0

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".

Deadline for manuscript submissions: closed (28 June 2024) | Viewed by 3006

Special Issue Editors

Dr. Elvira Rozhina

E-Mail Website
Guest Editor
Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml uramı 18, 420008 Kazan, Republic of Tatarstan, Russia
Interests: nanotoxicology; biogenic silver nanoparticles; 3D spheroids; halloysite nanotubes; cell culture
Special Issues, Collections and Topics in MDPI journals
Dr. Svetlana A. Konnova

E-Mail Website
Guest Editor
Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml urami 18, 420008 Kazan, Republic of Tatarstan, Russia
Interests: microbiology; hybrid systems; nanocomposite materials; clay minerals; oil-degrading bacteria
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Magnetic nanoparticles (MNPs) are spherical particles comprising various metals and their alloys (Fe, Ni, Co, etc.). They have diameters of 1–100 nm in size, a large surface area, colloidal stability, and unique optical properties. MNPs also possess great potential for use in targeted drug delivery, bioimaging, and cancer therapy. Due to the possibility of MNP functionalization with various ligands, they can be used for the magnetic separation of cells or biomolecules. Magnetic iron oxide nanoparticles are popular in biomedicine due to their high biocompatibility, ease of preparation, and optimal magnetic properties. Their small size, colloidal stability, and biological inertness allow them to be used as contrast agents for non-invasive imaging. In addition, the action of an external field on magnetic nanoparticles causes oscillations that flow into thermal energy; this is used for the induction of local hyperthermia, inhibiting the proliferation of cancer cells. In addition, by using magnetic nanoparticles, it is possible to obtain cellular substrates with a finely tuned architecture of surface nanotopography, allowing the effect of mechanical signals on cell growth and proliferation to be assessed.

Potential topics include, but are not limited to, the following:

  • Magnetic nanoparticles and targeted drug delivery;
  • Magnetic nanoparticles as instruments for nanotopography;
  • Magnetic nanoparticles for bioimaging;
  • Magnetic nanoparticles for cell and biomolecule separation;
  • Magnetic nanoparticles and non-invasive imaging;
  • Magnetic nanoparticles and nanocomposites.

Dr. Elvira Rozhina
Dr. Svetlana A. Konnova
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • magnetic nanoparticles and targeted drug delivery
  • magnetic nanoparticles as instruments for nanotopography
  • magnetic nanoparticles for bioimaging
  • magnetic nanoparticles for cell and biomolecule separation
  • magnetic nanoparticles and non-invasive imaging
  • magnetic nanoparticles and nanocomposites

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

19 pages, 4178 KiB  
Article
Toxicity of Large and Small Surface-Engineered Upconverting Nanoparticles for In Vitro and In Vivo Bioapplications
by Lucia Machová Urdzíková, Dana Mareková, Taras Vasylyshyn, Petr Matouš, Vitalii Patsula, Viktoriia Oleksa, Oleksandr Shapoval, Magda Vosmanská, David Liebl, Aleš Benda, Vít Herynek, Daniel Horák and Pavla Jendelová
Int. J. Mol. Sci. 2024, 25(10), 5294; https://doi.org/10.3390/ijms25105294 - 13 May 2024
Cited by 2 | Viewed by 1089
Abstract
In this study, spherical or hexagonal NaYF4:Yb,Er nanoparticles (UCNPs) with sizes of 25 nm (S-UCNPs) and 120 nm (L-UCNPs) were synthesized by high-temperature coprecipitation and subsequently modified with three kinds of polymers. These included poly(ethylene glycol) (PEG) and poly(N,N-dimethylacrylamide-co-2-aminoethylacrylamide) [P(DMA-AEA)] terminated [...] Read more.
In this study, spherical or hexagonal NaYF4:Yb,Er nanoparticles (UCNPs) with sizes of 25 nm (S-UCNPs) and 120 nm (L-UCNPs) were synthesized by high-temperature coprecipitation and subsequently modified with three kinds of polymers. These included poly(ethylene glycol) (PEG) and poly(N,N-dimethylacrylamide-co-2-aminoethylacrylamide) [P(DMA-AEA)] terminated with an alendronate anchoring group, and poly(methyl vinyl ether-co-maleic acid) (PMVEMA). The internalization of nanoparticles by rat mesenchymal stem cells (rMSCs) and C6 cancer cells (rat glial tumor cell line) was visualized by electron microscopy and the cytotoxicity of the UCNPs and their leaches was measured by the real-time proliferation assay. The comet assay was used to determine the oxidative damage of the UCNPs. An in vivo study on mice determined the elimination route and potential accumulation of UCNPs in the body. The results showed that the L- and S-UCNPs were internalized into cells in the lumen of endosomes. The proliferation assay revealed that the L-UCNPs were less toxic than S-UCNPs. The viability of rMSCs incubated with particles decreased in the order S-UCNP@Ale-(PDMA-AEA) > S-UCNP@Ale-PEG > S-UCNPs > S-UCNP@PMVEMA. Similar results were obtained in C6 cells. The oxidative damage measured by the comet assay showed that neat L-UCNPs caused more oxidative damage to rMSCs than all coated UCNPs while no difference was observed in C6 cells. An in vivo study indicated that L-UCNPs were eliminated from the body via the hepatobiliary route; L-UCNP@Ale-PEG particles were almost eliminated from the liver 96 h after intravenous application. Pilot fluorescence imaging confirmed the limited in vivo detection capabilities of the nanoparticles. Full article
(This article belongs to the Special Issue Magnetic Nanoparticles for Biomedical and Imaging Applications 2.0)
►▼ Show Figures

Figure 1

17 pages, 2950 KiB  
Article
Simplified Synthesis of the Amine-Functionalized Magnesium Ferrite Magnetic Nanoparticles and Their Application in DNA Purification Method
by Ágnes M. Ilosvai, Tímea B. Gerzsenyi, Emőke Sikora, Lajos Harasztosi, Ferenc Kristály, Béla Viskolcz, Csaba Váradi, Emma Szőri-Dorogházi and László Vanyorek
Int. J. Mol. Sci. 2023, 24(18), 14190; https://doi.org/10.3390/ijms241814190 - 16 Sep 2023
Viewed by 1459
Abstract
For pathogens identification, the PCR test is a widely used method, which requires the isolation of nucleic acids from different samples. This extraction can be based on the principle of magnetic separation. In our work, amine-functionalized magnesium ferrite nanoparticles were synthesized for this [...] Read more.
For pathogens identification, the PCR test is a widely used method, which requires the isolation of nucleic acids from different samples. This extraction can be based on the principle of magnetic separation. In our work, amine-functionalized magnesium ferrite nanoparticles were synthesized for this application by the coprecipitation of ethanolamine in ethylene glycol from Mg(II) and Fe(II) precursors. The conventional synthesis method involves a reaction time of 12 h (MgFe2O4-H&R MNP); however, in our modified method, the reaction time could be significantly reduced to only 4 min by microwave-assisted synthesis (MgFe2O4-MW MNP). A comparison was made between the amine-functionalized MgFe2O4 samples prepared by two methods in terms of the DNA-binding capacity. The experimental results showed that the two types of amine-functionalized magnesium ferrite magnetic nanoparticles (MNPs) were equally effective in terms of their DNA extraction yield. Moreover, by using a few minutes-long microwave synthesis, we obtained the same quality magnesium ferrite particles as those made through the long and energy-intensive 12-h production method. This advancement has the potential to improve and expedite pathogen identification processes, helping to better prevent the spread of epidemics. Full article
(This article belongs to the Special Issue Magnetic Nanoparticles for Biomedical and Imaging Applications 2.0)
►▼ Show Figures

Graphical abstract

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop