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Advances in Nano-Based Drug Delivery and Theranostic Systems

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 19

Special Issue Editors


E-Mail Website
Guest Editor
Institute for Quantitative Health Science and Engineering (IQ), Michigan State University, East Lansing, MI 48824, USA
Interests: nanomedicine; drug/gene delivery; molecular imaging; nano–bio interactions; atherosclerosis; cancer therapy

E-Mail Website
Guest Editor
Institute for Quantitative Health Science & Engineering (IQ), Michigan State University, East Lansing, MI 48824, USA
Interests: nanoparticle; cancer therapy; cancer imaging; immunotherapy; tumor microenvironment
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Special Issue Information

Dear Colleagues,

Recent advancements in nano-engineered materials have revolutionized drug delivery and theranostics in healthcare, enabling precision medicine with improved efficacy and reduced side effects. These nanoscale carriers enhance the bioavailability and stability of drugs, allowing for controlled and targeted release at specific sites. Lipid-based, polymeric, and inorganic nanoparticles facilitate the delivery of a wide range of therapeutics, including chemotherapy agents, RNA-based treatments, and biologics. Hybrid nanoparticles, engineered with dual functionality, enhance disease detection while ensuring precise treatment. Novel innovations integrate therapy with real-time diagnostics where nanoparticles are engineered to be functionalized with imaging agents, such as fluorophores, quantum dots, or magnetic nanoparticles, allowing simultaneous drug delivery and disease monitoring in various disease conditions. Additionally, stimuli-responsive nanoparticles facilitate the systemic release of drugs in response to physiological conditions, such as pH, temperature, or enzymes, thereby optimizing therapeutic outcomes. As nanotechnology advances, personalized medicine and targeted drug delivery systems will continue to evolve, revolutionizing healthcare with more effective treatments and improved patient outcomes. This Special Issue invites the submission of original research or review manuscripts that focus on nanoparticle-based drug delivery and theranostics in diseases, including but not limited to the following areas:

  • Response to external or internal stimuli in drug delivery;
  • Innovative theranostic nanoparticles for assessing treatment effectiveness;
  • Nanocarriers for antibody–drug conjugates;
  • Gene delivery systems;
  • Nanoparticle-assisted imaging to monitor disease conditions;
  • AI in predicting nanoparticle interactions for drug delivery optimization.

Dr. Mukesh Meher
Dr. Yapei Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanoparticles
  • smart drug/gene delivery
  • multifunctional nanoparticles
  • theranostics
  • targeted therapy
  • molecular imaging
  • cancer

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This special issue is now open for submission.
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