New Advances on Photosensitiser or Inhibitors Molecules for Cancer Treatment

Dear Colleagues, 

The photodynamic therapy concept in which low energy radiation is used on cancer cells with added DNA targeted photosensitizing molecules. The irradiation reaching these molecules enhances the generation of reactive oxygen species (ROS) which possesses cytotoxic effect on DNA. The use of photosensitizing molecules, which can intercalate with DNA helix through physical interactions instead of covalent bonds, prevents damage to normal cells and create radicals in cancer cells when submitted to radiation. But the action of photosensitizing molecules can be maximized if the DNA repair machinery is constrained by affecting the DNA repair proteins using inhibitor molecules that can reduce the effect of the repair and thus sensitize the cells for radiation therapy. This Special Issue of IJMS focuses on the latest developments on new photosensitiser or inhibitors molecules and on the effect of photosensitiser or inhibitors molecules encapsulated or not on biological molecules as DNA and/or DNA repair proteins and on cells in presence of radiation. This Special Issue, “New Advances on Photosensitiser or Inhibitors Molecules for Cancer Treatment”, invites review articles and full-length papers that explore the development or/and the role of photosensitiser or inhibitors molecules near of biological molecules or of cells in presence of radiation. Moreover, papers providing new insights into the development of new systems of encapsulation of these photosensitiser or inhibitors molecules for easier delivery to tumour area are also encouraged.

Dr. Maria Raposo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.