Antioxidants and Enzyme Inhibitors: Design, Synthesis and Action Mechanisms
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (20 April 2025) | Viewed by 718
Special Issue Editors
Interests: computational theoretical chemistry; conformational macromolecules; amino acids; peptides; nucleic acid; enzymes; metallo-enzymes; photosensitizer molecules
Special Issues, Collections and Topics in MDPI journals
Interests: computational chemistry; catalysis; antioxidants; bio-inorganic chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antioxidants are notoriously relevant species that prevent the oxidation of molecules, playing an important role in the control of oxidative stress in living systems. Due to the chemical structure, antioxidants can carry out their action by directly reacting with radicals or inhibiting the source of reactive species, such as transition metal ions or enzymes, saving cells and the macromolecules they are composed of from damages that can be the source of the onset of severe and inflammation-based diseases.
With respect to enzymes, the aim of this Special Issue is to provide an overview on the power of antioxidants in the inhibition of these biological catalysts, spanning in silico designs and synthesis of new compounds to the understanding of relevant action mechanisms. Both theoretical and experimental research devoted to accumulating the information repertoire useful for reinforcing treatments versus oxidative stress also implicated in many neurodegenerative processes are welcome, either in the case of identification of new compounds for new targets or in the use of already known species for new therapies.
Prof. Dr. Tiziana Marino
Dr. Mario Prejanò
Guest Editors
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Keywords
- antioxidants
- bioactive compounds
- oxidative stress
- reactive oxygen species
- enzyme inhibition
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