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Novel Polymeric Materials for Biomedical and Food Packaging Application

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: closed (20 February 2025) | Viewed by 996

Special Issue Editors


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Guest Editor
Department of Chemical Sciences, Università degli Studi di Catania, 95125 Catania, Italy
Interests: polyesters; synthesis; chemical modification; thermal properties; mechanical properties; barrier properties; biodegradability; food packaging; active packaging; diffusion; permeability; bio-based and biodegradable polymers; polymers from waste; nanocomposites; biocomposites; life cycle assessment
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Civil, Chemical, Environmental and Materials Engineering, University of Bologna, 40126 Bologna, Italy
Interests: polymer design; polymer synthesis and characterization; polymer modification; copolymerization; solid state properties; thermal properties and crystallization kinetics; mechanical characterization; bio-based monomers; bio-based polymers; nano-polymer; nanocomposites; gas barrier behaviour; polymer compostability; biopolymers for engineering tissue; polymeric for controlled drug delivery; biodegradation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Civil, Chemical, Environmental and Materials Engineering Department, University of Bologna, Via Terracini 28, 40131 Bologna, Italy
Interests: polyesters; polymer synthesis; chemical modification; thermal properties; mechanical properties; barrier properties; biodegradability; packaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

According to a United Nations (UN) estimation, the world population will grow enormously, reaching a peak in the 2080s. This prospect, combined with concerns about the sustainability of the global food system, has opened many discussions on food security as well as on the control of health conditions of the population. In this context, the agri-food and biomedical sectors are increasingly criticized for their harmful environmental impact and the high consumption of natural resources, and must face the current challenges of demographic growth and climate change, as reported in Agenda 2023 of the United Nations for Sustainable Development. 

This Special Issue aims to provide an overview of new strategies and solutions with the aim of developing new materials to be used in medical applications and in food packaging. Researchers are invited to contribute original research and review articles focusing on transdisciplinary aspects related to: i) identifying renewable resources to synthesize new materials; ii) the study of sustainable production processes and technologies for biobased and biodegradable materials; iii) exploiting wastes as a source of monomers for the synthesis of new biobased and biodegradable materials. 

The visibility and impact of these works will be promoted through the open-access platform of the journal.

Dr. Valentina Siracusa
Prof. Dr. Nadia Lotti
Dr. Giulia Guidotti
Guest Editors

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • bio-based polymers
  • biodegradable polymers
  • compostable polymers
  • packaging
  • biomedical application
  • polymer structure–properties relationship
  • polymers from wastes

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Published Papers (1 paper)

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Research

24 pages, 2395 KiB  
Article
Design and Characterization of Aromatic Copolyesters Containing Furan and Isophthalic Rings with Suitable Properties for Vascular Tissue Engineering
by Edoardo Bondi, Elisa Restivo, Michelina Soccio, Giulia Guidotti, Nora Bloise, Ilenia Motta, Massimo Gazzano, Marco Ruggeri, Lorenzo Fassina, Livia Visai, Gianandrea Pasquinelli and Nadia Lotti
Int. J. Mol. Sci. 2025, 26(13), 6470; https://doi.org/10.3390/ijms26136470 - 4 Jul 2025
Viewed by 371
Abstract
Cardiovascular diseases are responsible for a large number of severe disability cases and deaths worldwide. Strong research in this field has been extensively carried out, in particular for the associated complications, such as the occlusion of small-diameter (<6 mm) vessels. Accordingly, in the [...] Read more.
Cardiovascular diseases are responsible for a large number of severe disability cases and deaths worldwide. Strong research in this field has been extensively carried out, in particular for the associated complications, such as the occlusion of small-diameter (<6 mm) vessels. Accordingly, in the present research, two random copolyesters of poly(butylene 2,5-furandicarboxylate) (PBF) and poly(butylene isophthalate) (PBI), were successfully synthesized via two-step melt polycondensation and were thoroughly characterized from molecular, thermal, and mechanical perspectives. The copolymeric films displayed a peculiar thermal behavior, being easily processable in the form of films, although amorphous, with Tg close to room temperature. Their thermal stability was high in all cases, and from the mechanical point of view, the materials exhibited a high ultimate strength, together with values of elastic moduli tunable with the chemical composition. The long-term stability of these materials under physiological conditions was also demonstrated. Cytotoxicity was assessed using a direct contact assay with human umbilical vein endothelial cells (HUVECs). In addition, hemocompatibility was tested by evaluating the adhesion of blood components (such as the adsorption of human platelets and fibrinogen). As a result, a proper chemical design and, in turn, both the solid-state and functional properties, are pivotal in regulating cell behavior and opening new frontiers in the tissue engineering of soft tissues, including vascular tissues. Full article
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