Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
8.1
4.9
Journals
IJMS
Special Issues
Molecular Mechanisms, Pathophysiology and Therapeutic Strategies of Chronic Obstructive Pulmonary...
ijms-logo
Submit to Special Issue Submit Abstract to Special Issue Review for IJMS Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Molecular Mechanisms, Pathophysiology and Therapeutic Strategies of Chronic Obstructive Pulmonary Disease (COPD)

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 1797

Special Issue Editor

Dr. Shih-feng Liu

E-Mail Website
Guest Editor
1. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan
2. College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
3. Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan
Interests: Chronic Obstructive Pulmonary Disease (COPD); pathophysiology; novel therapeutic approaches; biomarkers; pulmonary rehabilitation; respiratory care

Special Issue Information

Dear Colleagues,

Chronic obstructive pulmonary disease (COPD) remains a major global health challenge, characterized by persistent respiratory symptoms and airflow limitation. Despite advances in understanding its pathophysiology, effective therapeutic options are still limited. This Special Issue aims to bridge the gap between current knowledge and innovative therapeutic approaches for COPD.

We invite researchers to submit original research articles, reviews, and short communications that explore novel insights into the molecular mechanisms of COPD, identify potential biomarkers for early diagnosis and prognosis, and discuss innovative therapeutic strategies. Contributions that focus on the role of inflammation, oxidative stress, and genetic factors in COPD pathogenesis are particularly welcome.

This Special Issue will provide a comprehensive overview of the latest advancements in COPD research, fostering collaboration and knowledge exchange among scientists, clinicians, and healthcare professionals.

Dr. Shih-feng Liu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chronic obstructive pulmonary disease (COPD)
  • pathophysiology
  • novel therapeutic approaches
  • biomarkers
  • pulmonary rehabilitation
  • inflammation
  • oxidative stress
  • genetic factors

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

14 pages, 598 KiB  
Review
Sex Differences in Chronic Obstructive Pulmonary Disease: Implications for Pathogenesis, Diagnosis, and Treatment
by Paulina Czarnota, Jamie L. MacLeod, Niya Gupta, Ani Manichaikul and Yun M. Shim
Int. J. Mol. Sci. 2025, 26(6), 2747; https://doi.org/10.3390/ijms26062747 - 18 Mar 2025
Viewed by 826
Abstract
Chronic obstructive pulmonary disease (COPD) is a leading chronic disease worldwide, with significant healthcare utilization, morbidity, and mortality. Irreversible airflow obstruction identified on spirometry establishes the diagnosis of COPD, but the disease entity encompasses a heterogeneous collection of lung diseases, including chronic bronchitis [...] Read more.
Chronic obstructive pulmonary disease (COPD) is a leading chronic disease worldwide, with significant healthcare utilization, morbidity, and mortality. Irreversible airflow obstruction identified on spirometry establishes the diagnosis of COPD, but the disease entity encompasses a heterogeneous collection of lung diseases, including chronic bronchitis and emphysema. Despite the enormous burden of COPD, there are no pharmacological therapies that slow its progression or reduce mortality, indicating the need for a deeper understanding. There are sex differences concerning COPD prevalence, pathology, and symptoms. Historically thought to primarily affect males, its effect on females has increased significantly over time due to a rising prevalence of smoking and exposure to harmful pollutants among females. Over the past decade, the age-adjusted prevalence of COPD has been consistently higher in females than in males. Despite this, the impacts of biological sex continue to be confusing and poorly defined. The primary goal of this review is to organize and collate sex-dependent factors that may contribute to disease differences in males and females, thereby identifying future research questions in this area. Full article
(This article belongs to the Special Issue Molecular Mechanisms, Pathophysiology and Therapeutic Strategies of Chronic Obstructive Pulmonary Disease (COPD))
►▼ Show Figures

Figure 1

36 pages, 1252 KiB  
Review
The Role of Inflammation in the Pathogenesis of Comorbidity of Chronic Obstructive Pulmonary Disease and Pulmonary Tuberculosis
by Stanislav Kotlyarov and Dmitry Oskin
Int. J. Mol. Sci. 2025, 26(6), 2378; https://doi.org/10.3390/ijms26062378 - 7 Mar 2025
Viewed by 755
Abstract
The comorbid course of chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis is an important medical and social problem. Both diseases, although having different etiologies, have many overlapping relationships that mutually influence their course and prognosis. The aim of the current review is [...] Read more.
The comorbid course of chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis is an important medical and social problem. Both diseases, although having different etiologies, have many overlapping relationships that mutually influence their course and prognosis. The aim of the current review is to discuss the role of different immune mechanisms underlying inflammation in COPD and pulmonary tuberculosis. These mechanisms are known to involve both the innate and adaptive immune system, including various cellular and intercellular interactions. There is growing evidence that immune mechanisms involved in the pathogenesis of both COPD and tuberculosis may jointly contribute to the tuberculosis-associated obstructive pulmonary disease (TOPD) phenotype. Several studies have reported prior tuberculosis as a risk factor for COPD. Therefore, the study of the mechanisms that link COPD and tuberculosis is of considerable clinical interest. Full article
(This article belongs to the Special Issue Molecular Mechanisms, Pathophysiology and Therapeutic Strategies of Chronic Obstructive Pulmonary Disease (COPD))
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop