Functional Materials for Bone Regeneration: Biomaterials and Cells

Dear Colleagues, 

Despite rapid advancements in regenerative therapy, bone regeneration for congenital and large bone defects is still challenging in the fields of dentistry, plastic surgery, and orthopedic surgery. Providing an optimal and ideal local environment for endogenous and exogenous cells is inevitable to overcome these challenges. Highly functional biomaterials enable the generation of a controlled environment. Furthermore, in vitro preconditioning of cells can facilitate the modulation of the local environment for bone regeneration. In this Special Issue, we aim to provide beneficial findings for the preparation and application of functional materials to effectively augment bone regeneration and elucidate novel mechanisms underlying the generation of an optimal environment for bone regeneration. Original research papers and mini- and full reviews are welcome. 

Potential topics include, but are not limited to the following:

• Modification of the scaffold or surface on materials for the spatiotemporal regulation of cell invasion and differentiation;
• Enhancement of the accuracy on the delivery and controlled-release of drugs;
• Regulation of anti-oxidant and anti-inflammatory effects;
• Effective methods to prepare cells for use in bone and osteochondral regeneration;
• Design and preparation of highly anti-bacterial materials;
• Cost-effective strategies for functionalizing biomaterials;
• Development of ecofriendly functional materials.

Dr. Yoshitomo Honda
Dr. Masahiro Yamada
Guest Editors

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