Special Issue "Embryo Implantation and Placental Development"
Deadline for manuscript submissions: 30 November 2020.
Interests: blastocyst; embryo implantation; placenta; trophoblast; placental development; pre-eclampsia; engineered nanomaterials; nano and microplastics
Human reproduction has been defined by many as a highly inefficient biological process. This is a consequence of the numerous coordinated and finely regulated molecular pathways which drive the different stages of embryonic development, from fertilization to implantation and placentation. Synchronization between the acquisition of blastocyst competence and uterine receptivity appears a limiting step in implantation, and the timely release of growth factors and cytokines is central for the establishment of a successful pregnancy. Over the last few years, many of the players involved in the regulation of such an intricated process have been identified, and their altered expression in pathological conditions has been recognized in some cases. The role of novel factors is emerging, possibly opening new paths for the interpretation of what is still defined as idiopathic infertility.
This Special Issue of the International Journal of Molecular Sciences aims at providing novel insights into the mechanisms of embryo implantation and placental development as well as at giving an overview of our current knowledge on the different signaling pathways regulating the early steps of implantation and placentation and on the pathological alterations which may impair the establishment of a physiological pregnancy. Submissions focused on each of these steps, which would contribute to present a comprehensive picture of what has been discovered and what should be further investigated, are welcome. Clinical and basic science contributions, consisting of original papers or reviews, will be equally considered.
Dr. Luisa Campagnolo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- endometrial epithelium
- immunology of implantation
- placental development
- placental barrier
- Epidermal growth factor-like domain 7 (EGFL7)