Curcumin Derivatives and Curcuminoids as Theranostic Agents in Alzheimer’s Disease

Dear Colleagues,

Curcumin, curcumin analogues, derivatives, and curcuminoids exert several biological activities, including certain interesting therapeutic properties against Alzheimer's disease (AD). Alzheimer’s disease is the most common neurodegenerative disease influencing the elderly population globally. At present, the therapeutic agents available do not offer a satisfactory cure to and/or treatment for AD. During the last decade, the scientific community has been focused on research into more efficient drugs to face neurological disorders. Furthermore, there is a need for more precise and accurate diagnostic agents. From this point of view, the invention of theranostic agents (both diagnostic and therapeutic) for neurodegenerative diseases will be of great significance, and the curcumin scaffold, which has been found to be a unique structure for a 2nd-generation Aβ PET tracer development, has the potential to play an important role in this.

This Special Issue, “Curcumin derivatives and Curcuminoids as Theranostic agents in Alzheimer’s Disease”, of the International Journal of Molecular Sciences will comprise a selection of research papers and reviews offering knowledge on the design, synthesis, development, properties and special structural characteristics of curcumin derivatives and curcuminoids as theranostic agents (both therapeutic and diagnostic), new entities inserted in clinical applications, in vitro and in vivo studies, strategies and identification of the key biological processes in which these agents will be implicated.

Prof. Dr. Dimitra Hadjipavlou-Litina
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.