EVs in Cross-Talk between Cancer and Immune Cells

Dear Colleagues,

Extracellular vesicles (EVs), their heterogeneity and role in modulation of anticancer immune response or cancer development are a rapidly growing field of research. These highly specific sentinels can transport diverse material (cargo), which may be incorporated both by cells in a local tumor microenvironment and in distant organs and tissues, affecting their functions. As EVs are now being considered a form of communication between cells, it is only fitting to discuss them in the aspect of cellular cross-talk, both in a paracrine and autocrine manner, especially in the context of tumor development. This open-access Special Issue will bring together original research and review articles on these interactions mediated by EVs, with emphasis on cross-talk between cancer and immune cells. 

Topics of this Special Issue include but are not limited to:

• Identification and new aspects of interactions of cancer and immune cells mediated by EVs of tumor and nontumor origin;
• Analysis of receptors involved in a cross-talk between cancer and immune cells mediated by EVs;
• Modification of immune cell functions and activation status by tumor-derived EVs, based on their specific cargo;
• Tumor promotion and development supported by EVs of immune-cell origin;
• Techniques for the analysis of specific interactions between cancer and immune cells mediated by EVs.

Prof. Dr. Jarek Baran
Guest Editor

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