Special Issue "Molecular Mechanisms of Pathogenesis, Prevention, and Therapy of COVID-19: Summarizing the Results of 2021"
Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 11937
Interests: immunology of inflammation; systemic inflammation; typical pathological processes
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Special Issue in International Journal of Molecular Sciences: Molecular Mechanisms of Pathogenesis, Prevention, and Therapy of COVID-19: Summarizing the Results of 2022
COVID-19 as a global public health challenge will eventually go down in history. However, the doors for a potential new generation of CoV infections, as well global epidemics of a different etiological nature, will remain open and that will lead to severe social consequences.
Thus, the time has come for preliminary analysis and generalization of the lessons learned from SARS-CoV-2.
Firstly, this concerns the separation of the unique and distinctive mechanisms of SARS-CoV-2 invasion from the general patterns of the infectious processes and the development of critical complications. The latter concerns the characteristics of not only the general molecular mechanisms of various pathologies but also the integral laws of pathology (models of pathological systems). We will inevitably face the consequences whether these issues are resolved.
Secondly, this applies to general strategies of viral invasions, targeted suppression of infectious agent infects via mechanisms of innate and adaptive host immunity, and the reorientation of these mechanisms against the organism during the development of systemic inflammation.
Thus, it is advisable to reconsider the data of both applied and general principles of pathogenetic therapy, to systematize the analysis of genetic and environmental risk factors for CoV infections, and the role of comorbid diseases in them.
We hope that the planned special issue "Molecular Mechanisms of Pathogenesis, Prevention, and Therapy of COVID-19: Summarizing the Results of 2021" will be a significant step towards solving these pressing problems.
Prof. Dr. Evgenii Gusev
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- typical pathological processes