Molecular Insights into Hepatocellular Carcinoma: From Carcinogenesis to Liver Transplantation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 93
Special Issue Editor
Interests: molecular mechanisms of carcinogenesis; metastasis and chemoresistance of hepatocellular carcinoma; molecular targets linking acute phase hepatic injury; late phase hepatocellular carcinoma recurrence; liver transplantation
Special Issue Information
Dear Colleagues,
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, arising from complex molecular mechanisms involving chronic inflammation, cirrhosis, viral hepatitis, genetic and epigenetic alterations, and metabolic dysfunction. Despite advances in early detection and treatment, HCC remains a significant clinical challenge due to its high recurrence rate and limited therapeutic options for advanced stages. This Special Issue will explore the comprehensive molecular pathogenesis of HCC, from early carcinogenic events to immune escape, progression, metastasis, therapy responses, and resistance to liver transplantation. By integrating cutting-edge research, this Special Issue aims to bridge fundamental science and clinical applications, fostering advancements in HCC understanding and precision oncology. We invite submissions of original research and review articles that contribute to this Special Issue, “Molecular Insights into Hepatocellular Carcinoma: From Carcinogenesis to Liver Transplantation”.
Your contributions are indispensable to the success of this initiative.
Dr. Kevin Tak-Pan Ng
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- hepatocarcinogenesis
- molecular pathogenesis
- tumor microenvironment
- metabolic dysfunction-associated fatty liver disease (MAFLD)
- metastasis
- genetic and epigenetic alterations
- biomarkers
- precision oncology
- targeted therapy
- immunotherapy
- therapy resistance
- immune escape
- tumor recurrence
- transplant oncology
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