Special Issue "Bioluminescent and Fluorescent Proteins: Molecular Mechanisms and Modern Applications"
Deadline for manuscript submissions: closed (20 December 2020).
Interests: bioluminescent and fluorescent proteins; molecular mechanism of bioluminescence; structure of bioluminescent proteins; bioluminescent analysis and imaging; BRET technologies
Special Issues and Collections in MDPI journals
Bioluminescence, a natural phenomenon of visible light emission by living organisms, has been found in numerous terrestrial and marine organisms. The study of bioluminescent reactions in organisms has revealed a specific feature—the mechanisms underlying light emission considerably differ in species of different taxa. Both the substrates and cofactors involved in bioluminescence reactions as well as the enzymes catalyzing these reactions have turned out to be peculiar. In addition to luciferases, many bioluminescence systems contain “antenna” proteins, such as Green fluorescent protein (GFP), which e.g., modulate the bioluminescence color by means of energy transfer. Although investigation of bioluminescence and fluorescence proteins is undoubtedly of fundamental interest, the main driving force that has attracted researchers to this topic is the broad analytical potential of bioluminescent proteins. Currently, there are no fields of biology or medicine where bioluminescence could not be widely used. This Special Issue of the International Journal of Molecular Science is devoted to experimental and theoretical studies on functioning mechanisms of bioluminescent proteins from various organisms, the proteins involved in bioluminescence (the lumazine protein, GFP and GPF-like proteins, and the enzymes participating in the synthesis of substrates), novel assays with the use of these proteins, and applications of these proteins in experimental biology and medicine. We invite authors to present their latest research in related fields.
Dr. Eugene S. Vysotski
Manuscript Submission Information
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- GFP-like proteins
- immuno and hybridization assays
- BRET and FRET assays