Adipokines, Myokines and Physical Exercise in Health and Disease 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 17336
Special Issue Editors
Interests: inflammatory bowel diseases; colitis; intestinal permeability; leaky gut; intestinal alkaline phosphatase; physical exercise; muscle fat crosstalk; myokines; adipokines
Special Issues, Collections and Topics in MDPI journals
Interests: brain–gut axis; experimental colitis; intestinal permeability; inflammatory bowel diseases; proinflammatory cytokines; adipokines; myokines; lipopolysaccharide; microbiota; obesity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Exercise has been shown to have a great impact on human life expectancy due to improved metabolic parameters mainly in obese individuals. However, whether exercises affect the course of various diseases in humans is very intriguing and should be further defined. In this context, physical activity and nutrition seem to be important components in optimizing human health benefits. Both adipose tissue and skeletal muscle are considered hormonal organs because of their ability to produce and secrete several bioactive peptides (e.g., myokines and adipokines). Recently, the protective activity of myokines, such as irisin, and adipokines, such as adiponectin or resistin, has been underlined. In addition, the beneficial effect of exercise of varying intensity may depend on adipokines released from adipose tissue and myokines released from working skeletal muscles, which corresponds to their therapeutic effects against various disorders associated not only with metabolic diseases, but also with other body systems, including cardiovascular and pulmonary systems, digestive tract, and nervous system. Although it is well accepted that exercise can induce changes in the composition and functioning of the intestinal microflora that are associated with the appearance of several pathological disorders, including obesity, diabetes, and cancer, the contribution of microbiota to the regulation of the myokine-adipokine profile and the function of these peptides remains largely unknown and requires further research in experimental animal models and humans.
Thus, this Special Issue entitled 'Adipokines, Myokines, and Exercise in Health and Disease' will publish experimental data and reviews on this innovative approach to this topic. Topics related to both original and reviewed articles on the impact of exercise on disease and health presented in experimental and clinical studies with an emphasis on physiological mediators and pharmacological agents are welcome.
Prof. Dr. Jan Bilski
Prof. Dr. Tomasz Brzozowski
Guest Editors
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